Evidence map›Paper›PMID 29361971›Full record

ArticleParasites & vectors2018

Multiflora rose invasion amplifies prevalence of Lyme disease pathogen, but not necessarily Lyme disease risk.

Solny A Adalsteinsson, W Gregory Shriver, Andrias Hojgaard, Jacob L Bowman, Dustin Brisson, Vincent D'Amico, Jeffrey J Buler

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Parasites & vectors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Wavyleaf basketgrass (mSphere · 2026
    Article
  3. Article
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  5. Article
  6. HumanPathogens (Basel, Switzerland) · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Solny A AdalsteinssonDepartment of Entomology and Wildlife Ecology, University of Delaware, Newark, DE, USA. solny.adalsteinsson@wustl.edu.
W Gregory ShriverDepartment of Entomology and Wildlife Ecology, University of Delaware, Newark, DE, USA.
Andrias HojgaardDivision of Vector-Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, CO, USA.
Jacob L BowmanDepartment of Entomology and Wildlife Ecology, University of Delaware, Newark, DE, USA.
Dustin BrissonDepartment of Biology, University of Pennsylvania, Philadelphia, PA, USA.
Vincent D'AmicoNorthern Research Station, USDA Forest Service, Newark, DE, USA.
Jeffrey J BulerDepartment of Entomology and Wildlife Ecology, University of Delaware, Newark, DE, USA.

Funding

Division of Environmental Biology 1354184University of Delaware Graduate Research Fellowship
6 · The paper itself

Abstract

backgroundForests in urban landscapes differ from their rural counterparts in ways that may alter vector-borne disease dynamics. In urban forest fragments, tick-borne pathogen prevalence is not well characterized; mitigating disease risk in densely-populated urban landscapes requires understanding ecological factors that affect pathogen prevalence. We trapped blacklegged tick (Ixodes scapularis) nymphs in urban forest fragments on the East Coast of the United States and used multiplex real-time PCR assays to quantify the prevalence of four zoonotic, tick-borne pathogens. We used Bayesian logistic regression and WAIC model selection to understand how vegetation, habitat, and landscape features of urban forests relate to the prevalence of B. burgdorferi (the causative agent of Lyme disease) among blacklegged ticks.

resultsIn the 258 nymphs tested, we detected Borrelia burgdorferi (11.2% of ticks), Borrelia miyamotoi (0.8%) and Anaplasma phagocytophilum (1.9%), but we did not find Babesia microti (0%). Ticks collected from forests invaded by non-native multiflora rose (Rosa multiflora) had greater B. burgdorferi infection rates (mean = 15.9%) than ticks collected from uninvaded forests (mean = 7.9%). Overall, B. burgdorferi prevalence among ticks was positively related to habitat features (e.g. coarse woody debris and total understory cover) favorable for competent reservoir host species.

conclusionsUnderstory structure provided by non-native, invasive shrubs appears to aggregate ticks and reservoir hosts, increasing opportunities for pathogen transmission. However, when we consider pathogen prevalence among nymphs in context with relative abundance of questing nymphs, invasive plants do not necessarily increase disease risk. Although pathogen prevalence is greater among ticks in invaded forests, the probability of encountering an infected tick remains greater in uninvaded forests characterized by thick litter layers, sparse understories, and relatively greater questing tick abundance in urban landscapes.

Indexed as

Introduced SpeciesRosaAnaplasma phagocytophilumAnimalsBabesia microtiBorrelia burgdorferiDisease ReservoirsEcosystemForestsIxodesLyme DiseaseMultiplex Polymerase Chain ReactionNymphPrevalenceRisk FactorsTick-Borne DiseasesAnaplasma phagocytophilumBabesia microtiBorrelia burgdorferiBorrelia miyamotoiForest fragmentInvasive speciesLyme diseaseUrbanization

Identifiers

PMID29361971
PMCPMC5781316

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.