Evidence map›Paper›PMID 29361963›Full record

ReviewParasites & vectors2018

Diagnostic tools in childhood malaria.

Amirah Amir, Fei-Wen Cheong, Jeremy R De Silva, Yee-Ling Lau

Abstract readReview
In one paragraph

Review in Parasites & vectors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. A case of babesiosis in a returning traveller.Southern African journal of infectious diseases · 2024
    Article
  6. Performance ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2023
    Article
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Amirah AmirDepartment of Parasitology, Faculty of Medicine, University Malaya, 50603, Kuala Lumpur, Malaysia.
Fei-Wen CheongDepartment of Parasitology, Faculty of Medicine, University Malaya, 50603, Kuala Lumpur, Malaysia.
Jeremy R De SilvaDepartment of Parasitology, Faculty of Medicine, University Malaya, 50603, Kuala Lumpur, Malaysia.
Yee-Ling LauDepartment of Parasitology, Faculty of Medicine, University Malaya, 50603, Kuala Lumpur, Malaysia. lauyeeling@um.edu.my.

Funding

Research Mentoring and Building Capacity of underrepresented Minority Research Scientists in India.D43TW010540 · FIC · YALE UNIVERSITY · PI MICHELE BARRY, Eva Harris · 2017 to 2026
$15.5M
FIC NIH HHS D43 TW010540FIC NIH HHS D43TW010540Universiti Malaya BK005-2017Universiti Malaya BK013-2016
6 · The paper itself

Abstract

Every year, millions of people are burdened with malaria. An estimated 429,000 casualties were reported in 2015, with the majority made up of children under five years old. Early and accurate diagnosis of malaria is of paramount importance to ensure appropriate administration of treatment. This minimizes the risk of parasite resistance development, reduces drug wastage and unnecessary adverse reaction to antimalarial drugs. Malaria diagnostic tools have expanded beyond the conventional microscopic examination of Giemsa-stained blood films. Contemporary and innovative techniques have emerged, mainly the rapid diagnostic tests (RDT) and other molecular diagnostic methods such as PCR, qPCR and loop-mediated isothermal amplification (LAMP). Even microscopic diagnosis has gone through a paradigm shift with the development of new techniques such as the quantitative buffy coat (QBC) method and the Partec rapid malaria test. This review explores the different diagnostic tools available for childhood malaria, each with their characteristic strengths and limitations. These tools play an important role in making an accurate malaria diagnosis to ensure that the use of anti-malaria are rationalized and that presumptive diagnosis would only be a thing of the past.

Indexed as

AntimalarialsChildChild, PreschoolDiagnostic ErrorsDiagnostic Tests, RoutineHumansMalariaMicroscopyMolecular Diagnostic TechniquesNucleic Acid Amplification TechniquesReal-Time Polymerase Chain ReactionSensitivity and SpecificityAntimalarialsChildhoodDiagnosisMalariaMicroscopyPCRRDT

Identifiers

PMID29361963
PMCPMC5781272

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.