Evidence map›Paper›PMID 29361551›Full record

ArticleJournal of cell science2018

Characterization of a novel RP2-OSTF1 interaction and its implication for actin remodelling.

Rodanthi Lyraki, Mandy Lokaj, Dinesh C Soares, Abigail Little, Matthieu Vermeren, Joseph A Marsh, Alfred Wittinghofer, Toby Hurd

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cell science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 46 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Rodanthi LyrakiMRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK.ORCID 0000-0003-4974-5567
Mandy LokajStructural Biology Group, Max-Planck Institut für Molekulare Physiologie, Abteilung Strukturelle Biologie, Otto-Hahn-Str. 11, 44227 Dortmund, Germany.
Dinesh C SoaresMRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK.ORCID 0000-0001-7557-0495
Abigail LittleMRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK.
Matthieu VermerenMRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK.ORCID 0000-0003-3584-0387
Joseph A MarshMRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK.ORCID 0000-0003-4132-0628
Alfred WittinghoferStructural Biology Group, Max-Planck Institut für Molekulare Physiologie, Abteilung Strukturelle Biologie, Otto-Hahn-Str. 11, 44227 Dortmund, Germany.ORCID 0000-0002-5800-0236
Toby HurdMRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK toby.hurd@igmm.ed.ac.uk.ORCID 0000-0003-1533-1171
Western General Hospital · GBMax Planck Institute of Molecular Physiology · DE

Funding

Medical Research Council MR/M02122X/1
6 · The paper itself

Abstract

Retinitis pigmentosa 2 (

Indexed as

ActinsADP-Ribosylation FactorsBinding SitesCell LineCell MembraneCell MovementCiliaEye ProteinsGTP-Binding ProteinsHEK293 CellsHumansIntracellular Signaling Peptides and ProteinsMembrane ProteinsMolecular Docking SimulationMyosin Type IProtein BindingActinsADP-Ribosylation FactorsARL3 protein, humanEye ProteinsGTP-Binding ProteinsIntracellular Signaling Peptides and ProteinsMembrane ProteinsMYO1E protein, humanMyosin Type IOSTF1 protein, humanProteinsRP2 protein, humanActinOSTF1Retinitis pigmentosaRP2

Identifiers

PMID29361551
PMCPMC5868953
OpenAlexW2783665516

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.