Evidence map›Paper›PMID 29361539›Full record

ArticleJournal of cell science2018

Glycans modify mesenchymal stem cell differentiation to impact on the function of resulting osteoblasts.

Katherine M Wilson, Alistair M Jagger, Matthew Walker, Estere Seinkmane, James M Fox, Roland Kröger, Paul Genever, Daniel Ungar

Open access · hybridAbstract read
In one paragraph

Article in Journal of cell science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. MSTNCells · 2026
    Article
  3. Article
  4. Article
  5. Regulation of Glycosylation in Bone Metabolism.International journal of molecular sciences · 2024
    Review
  6. Review
  7. AFrontiers in genetics · 2023
    Article
  8. Review
  9. Article
  10. Article
  11. Cell Surface and Functional Features of Cortical Bone Stem Cells.International journal of molecular sciences · 2021
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Katherine M WilsonDepartment of Biology, University of York, York YO10 5DD, UK.
Alistair M JaggerDepartment of Biology, University of York, York YO10 5DD, UK.
Matthew WalkerDepartment of Biology, University of York, York YO10 5DD, UK.
Estere SeinkmaneDepartment of Biology, University of York, York YO10 5DD, UK.ORCID 0000-0002-3636-4709
James M FoxDepartment of Biology, University of York, York YO10 5DD, UK.
Roland KrögerDepartment of Physics, University of York, York YO10 5DD, UK.ORCID 0000-0002-5070-0297
Paul GeneverDepartment of Biology, University of York, York YO10 5DD, UK.ORCID 0000-0002-5730-8976
Daniel UngarDepartment of Biology, University of York, York YO10 5DD, UK dani.ungar@york.ac.uk.ORCID 0000-0002-9852-6160
University of York · GB

Funding

Arthritis Research UK 19429Versus Arthritis 19429
6 · The paper itself

Abstract

Glycans are inherently heterogeneous, yet glycosylation is essential in eukaryotes, and glycans show characteristic cell type-dependent distributions. By using an immortalized human mesenchymal stromal cell (MSC) line model, we show that both

Indexed as

Calcification, PhysiologicCell DifferentiationCell LineGlycosylationGolgi ApparatusHumansMesenchymal Stem CellsOsteoblastsOsteogenesisPhosphatidylinositol 3-KinasesPolysaccharidesProto-Oncogene Proteins c-aktPhosphatidylinositol 3-KinasesPolysaccharidesProto-Oncogene Proteins c-aktGlycan processingHydroxyapatiteKifunensineOsteogenesisPI3K signalling

Identifiers

PMID29361539
PMCPMC5868951
OpenAlexW2783248069

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.