Evidence map›Paper›PMID 29361536›Full record

ArticleJournal of cell science2018

FGF2-dependent mesenchyme and laminin-111 are niche factors in salivary gland organoids.

Zeinab F Hosseini, Deirdre A Nelson, Nicholas Moskwa, Lauren M Sfakis, James Castracane, Melinda Larsen

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cell science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
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  15. Salivary Gland Bioengineering.Bioengineering (Basel, Switzerland) · 2023
    Review
  16. Review
  17. Article
  18. Review
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Zeinab F HosseiniDepartment of Biological Sciences, University at Albany, State University of New York, Albany, NY 12222, USA.
Deirdre A NelsonDepartment of Biological Sciences, University at Albany, State University of New York, Albany, NY 12222, USA.
Nicholas MoskwaDepartment of Biological Sciences, University at Albany, State University of New York, Albany, NY 12222, USA.
Lauren M SfakisColleges of Nanoscale Sciences and Engineering, SUNY Polytechnic Institute, 257 Fuller Rd, Albany, NY 12203, USA.
James CastracaneColleges of Nanoscale Sciences and Engineering, SUNY Polytechnic Institute, 257 Fuller Rd, Albany, NY 12203, USA.
Melinda LarsenDepartment of Biological Sciences, University at Albany, State University of New York, Albany, NY 12222, USA mlarsen@albany.edu.ORCID 0000-0002-5026-2012
Albany State University · USBoston Scientific (United States) · USSUNY Polytechnic Institute · US

Funding

Engineering Functional Salivary Glands Using Micropatterned ScaffoldsR01DE022467 · NIDCR · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI CASTRACANE, JAMES, LARSEN, MELINDA · 2012 to 2016
$2.4M
Engineering Functioning Salivary Glands Using Micropatterned ScaffoldsR56DE022467 · NIDCR · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI CASTRACANE, JAMES, LARSEN, MELINDA · 2017 to 2017
$653k
EXTRAMURAL RESEARCH FACILITIES CONSTRUCTIONC06RR015464 · NCRR · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI WICK-PELLETIER, JOAN · 2000 to 2000
$620k
NCRR NIH HHS C06 RR015464NIDCR NIH HHS R01 DE022467NIDCR NIH HHS R56 DE022467
6 · The paper itself

Abstract

Epithelial progenitor cells are dependent upon a complex 3D niche to promote their proliferation and differentiation during development, which can be recapitulated in organoids. The specific requirements of the niche remain unclear for many cell types, including the proacinar cells that give rise to secretory acinar epithelial cells that produce saliva. Here, using

Indexed as

Acinar CellsAnimalsAquaporin 5Cell DifferentiationCell ProliferationEpidermal Growth FactorEpithelial CellsFibroblast Growth Factor 2Gene Expression Regulation, DevelopmentalGene Knockdown TechniquesLamininMesodermMiceNIH 3T3 CellsOrganoidsPrimary Cell CultureAqp5 protein, mouseAquaporin 5Epidermal Growth FactorFibroblast Growth Factor 2LamininFGF2MesenchymeOrganoidProgenitorSubmandibular salivary gland

Identifiers

PMID29361536
PMCPMC5868949
OpenAlexW2782816981

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.