Evidence map›Paper›PMID 29361518›Full record

ArticleDisease models & mechanisms2018

The IgCAM CLMP regulates expression of Connexin43 and Connexin45 in intestinal and ureteral smooth muscle contraction in mice.

Hanna Langhorst, René Jüttner, Dieter Groneberg, Azadeh Mohtashamdolatshahi, Laura Pelz, Bettina Purfürst, Kai M Schmidt-Ott, Andreas Friebe, Fritz G Rathjen

Open access · goldAbstract read
In one paragraph

Article in Disease models & mechanisms, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

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  14. Whole-Exome Sequencing Identified NovelFrontiers in genetics · 2020
    Article
  15. Smooth muscle contractility causes the gut to grow anisotropically.Journal of the Royal Society, Interface · 2019
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Hanna LanghorstMax-Delbrück-Center for Molecular Medicine, DE-13092 Berlin, Germany.
René JüttnerMax-Delbrück-Center for Molecular Medicine, DE-13092 Berlin, Germany.
Dieter GronebergPhysiologisches Institut der Universität Würzburg, Röntgenring 9, DE-97070 Würzburg, Germany.
Azadeh MohtashamdolatshahiMax-Delbrück-Center for Molecular Medicine, DE-13092 Berlin, Germany.
Laura PelzMax-Delbrück-Center for Molecular Medicine, DE-13092 Berlin, Germany.
Bettina PurfürstMax-Delbrück-Center for Molecular Medicine, DE-13092 Berlin, Germany.
Kai M Schmidt-OttCharité-Universitätsmedizin Berlin, Department of Nephrology, Charitéplatz 1, DE-10117 Berlin, Germany.
Andreas FriebePhysiologisches Institut der Universität Würzburg, Röntgenring 9, DE-97070 Würzburg, Germany.
Fritz G RathjenMax-Delbrück-Center for Molecular Medicine, DE-13092 Berlin, Germany Rathjen@mdc-berlin.de.ORCID 0000-0001-5351-613X
Max Delbrück Center · DEUniversity of Würzburg · DECharité - Universitätsmedizin Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CAR-like membrane protein (CLMP), an immunoglobulin cell adhesion molecule (IgCAM), has been implicated in congenital short-bowel syndrome in humans, a condition with high mortality for which there is currently no cure. We therefore studied the function of CLMP in a

Indexed as

Muscle ContractionAnimalsBody WeightCalcium SignalingCell CommunicationConnexin 43ConnexinsCoxsackie and Adenovirus Receptor-Like Membrane ProteinFemaleHumansHydronephrosisIntestinesMice, Inbred C57BLMuscle, SmoothMyocytes, Smooth MusclePeristalsisConnexin 43connexin 45ConnexinsCoxsackie and Adenovirus Receptor-Like Membrane ProteinCell adhesionCLMPCongenital short-bowel syndromeConnexin43Connexin45HydronephrosisIgCAMPeristalsisSmooth muscle cells

Identifiers

PMID29361518
PMCPMC5894946
OpenAlexW2783690806

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.