Evidence map›Paper›PMID 29361373›Full record

ArticleUltrasound in medicine & biology2018

Ultrasound-Mediated Microbubble Destruction Suppresses Melanoma Tumor Growth.

Kee W Jang, Dongrim Seol, Lei Ding, Tae-Hong Lim, Joseph A Frank, James A Martin

Open access · bronzeAbstract read
In one paragraph

Article in Ultrasound in medicine & biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Application of Ultrasound Combined with Microbubbles for Cancer Therapy.International journal of molecular sciences · 2022
    Review
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Kee W JangFrank Laboratory, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA. Electronic address: kee.jang@nih.gov.
Dongrim SeolDepartment of Orthopaedics and Rehabilitation, The University of Iowa, Iowa City, Iowa, USA.
Lei DingJiangnan University Wuxi Medical School, Wuxi, Jiangsu, China.
Tae-Hong LimDepartment of Biomedical Engineering, The University of Iowa, Iowa City, Iowa, USA.
Joseph A FrankFrank Laboratory, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA; National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, USA.
James A MartinDepartment of Orthopaedics and Rehabilitation, The University of Iowa, Iowa City, Iowa, USA.
University of Iowa · USJiangnan University · CNNational Institute of Biomedical Imaging and Bioengineering · USNational Institutes of Health Clinical Center · US

Funding

Preclinical high intensity focused ultrasound: mechanisms and applicationsZIACL040014 · CLC · CLINICAL CENTER · PI FRANK, JOSEPH · 2009 to 2025
$0k
Intramural NIH HHS Z99 CL999999Intramural NIH HHS ZIA CL040014
6 · The paper itself

Abstract

Melanoma is one of the most aggressive types of cancer, and its incidence has increased rapidly in the past few decades. In this study, we investigated a novel treatment approach, the use of low-intensity ultrasound (2.3 W/cm

Indexed as

MicrobubblesAlbuminsAnimalsCell DeathContrast MediaDisease Models, AnimalFemaleFluorocarbonsMelanomaMiceMice, Inbred C57BLUltrasonicsAlbuminsContrast MediaFluorocarbonsFS 069Low-intensity ultrasoundMelanomaMicrobubblesOptison microbubblesUltrasound-mediated microbubble destruction

Identifiers

PMID29361373
PMCPMC5826859
OpenAlexW2790221425

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.