Evidence map›Paper›PMID 29361236›Full record

ArticleAmerican journal of respiratory cell and molecular biology2018

β-Arrestin-2-Dependent Signaling Promotes CCR4-mediated Chemotaxis of Murine T-Helper Type 2 Cells.

Rui Lin, Yeon Ho Choi, David A Zidar, Julia K L Walker

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory cell and molecular biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Targeting CXCR1/2 suppresses TThe journal of allergy and clinical immunology. Global · 2026
    Article
  3. Cardiomyocyte β-arrestins mediate inflammation and cGAS-STING activation in CVB3 viral myocarditis.American journal of physiology. Heart and circulatory physiology · 2026
    Article
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  16. Review
  17. Assessment of Lymphocyte Migration in an Ex Vivo Transmigration System.Journal of visualized experiments : JoVE · 2019
    Article
  18. Therapeutic Potential of Targeting ß-Arrestin.Frontiers in pharmacology · 2019
    Review
  19. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Rui Lin1 Duke University Division of Pulmonary Medicine and.
Yeon Ho Choi1 Duke University Division of Pulmonary Medicine and.
David A Zidar2 Harrington Heart and Vascular Institute, University Hospitals Case Medical Center, Case Western Reserve University School of Medicine, Cleveland, Ohio.
Julia K L Walker1 Duke University Division of Pulmonary Medicine and.
Duke University · USUniversity Hospitals Cleveland Medical Center · US

Funding

Optimizing Beta-Adrenoceptor Signaling Bias in AsthmaR01AI110007 · NIAID · DUKE UNIVERSITY · PI BOND, RICHARD AGUSTIN, PENN, RAYMOND B. · 2014 to 2018
$3.2M
T cell function in asthma depends on a novel signaling pathwayR01HL084123 · NHLBI · DUKE UNIVERSITY · PI WALKER, JULIA K L · 2008 to 2012
$1.9M
NHLBI NIH HHS R01 HL084123NIAID NIH HHS R01 AI110007
6 · The paper itself

Abstract

Allergic asthma is a complex inflammatory disease that leads to significant healthcare costs and reduction in quality of life. Although many cell types are implicated in the pathogenesis of asthma, CD4

Indexed as

AmidesAnimalsbeta-Arrestin 2CD4-Positive T-LymphocytesCell DifferentiationCell MovementChemokine CCL22ChemotaxisEnzyme InhibitorsMaleMice, KnockoutPyridinesReceptors, CCR4Signal TransductionTh2 CellsAmidesArrb2 protein, mousebeta-Arrestin 2Ccl22 protein, mouseCcr4 protein, mouseChemokine CCL22Enzyme InhibitorsPyridinesReceptors, CCR4Y 27632asthmaCCR4chemotaxisT-helper type 2 cellβ-arrestin-2–dependent signaling

Identifiers

PMID29361236
PMCPMC6002661
OpenAlexW2792016711

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.