ReviewAnnals of the American Thoracic Society2018
Intrapleural Fibrinolytic Therapy for Empyema and Pleural Loculation: Knowns and Unknowns.
Review in Annals of the American Thoracic Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- The LTI-01-2001 phase 2a trial of intrapleural LTI-01 in patients with infected, non-draining pleural effusions.Respiratory research · 2026Trial
- Role of Video-Assisted Thoracoscopic Surgery in Acute Empyema in Children: A Retrospective Analysis.Cureus · 2025Article
- Research Priorities for Malignant Pleural Organization with Loculation and Failed Drainage.Cells · 2025Review
- Pleural Space Diseases and Their Management: What is the Role of Intrapleural Fibrinolytic Therapy?The American surgeon · 2025Review
- Intrapleural Fibrinolytic Interventions for Retained Hemothoraces in Rabbits.International journal of molecular sciences · 2024Article
- A Novel Rabbit Model of Retained Hemothorax with Pleural Organization.International journal of molecular sciences · 2023Article
- Targeting the PAI-1 Mechanism with a Small Peptide Increases the Efficacy of Alteplase in a Rabbit Model of Chronic Empyema.Pharmaceutics · 2023Article
- Is the Urokinase Plasminogen Activator/Plasminogen Activator Inhibitor-1 Ratio a Marker of Sonographic Septations in Pleural Infection?American journal of respiratory and critical care medicine · 2023Article
- PAI-1 Drives Septation and Clinical Outcomes in Pleural Infection.American journal of respiratory and critical care medicine · 2023Article
- Article
- Update on Novel Targeted Therapy for Pleural Organization and Fibrosis.International journal of molecular sciences · 2022Review
- The Contribution of the Urokinase Plasminogen Activator and the Urokinase Receptor to Pleural and Parenchymal Lung Injury and Repair: A Narrative Review.International journal of molecular sciences · 2021Review
- From Bedside to the Bench-A Call for Novel Approaches to Prognostic Evaluation and Treatment of Empyema.Frontiers in pharmacology · 2021Review
- Intrapleural use of urokinase and DNase in pleural infections managed with repeated thoracentesis: A comparative cohort study.PloS one · 2021Article
- Hemothorax: A Review of the Literature.Clinical pulmonary medicine · 2020Article
- Phase 1 trial of intrapleural LTI-01; single chain urokinase in complicated parapneumonic effusions or empyema.JCI insight · 2019Article
- Article
- Small-bore catheter is more than an alternative to the ordinary chest tube for pleural drainage.Lung India : official organ of Indian Chest SocietyArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.