Evidence map›Paper›PMID 29361102›Full record

ArticleInflammatory bowel diseases2018

Sexual Dysfunction in Men With Inflammatory Bowel Disease: A New IBD-Specific Scale.

Aoibhlinn O'Toole, Punyanganie S de Silva, Linda G Marc, Christine A Ulysse, Marcia A Testa, Amanda Ting, Alan Moss, Josh Korzenik, Sonia Friedman

Open access · greenAbstract readMulticenter StudyValidation Study
In one paragraph

Article in Inflammatory bowel diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
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  6. Multidimensional fatigue mediates the relationship between sexual quality of life and perceived stress in patients with inflammatory bowel disease.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2025
    Article
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  9. Associations with sexual dysfunction among a Canadian cohort with inflammatory bowel disease.Journal of the Canadian Association of Gastroenterology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Aoibhlinn O'TooleCenter for Crohn's and Colitis, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Punyanganie S de SilvaCenter for Crohn's and Colitis, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Linda G MarcHarvard School of Public Health, Department of Biostatistics, Boston, Massachusetts, USA.
Christine A UlysseHarvard School of Public Health, Department of Biostatistics, Boston, Massachusetts, USA.
Marcia A TestaHarvard School of Public Health, Department of Biostatistics, Boston, Massachusetts, USA.
Amanda TingHarvard Medical School, Harvard University, Boston, Massachusetts, USA.
Alan MossHarvard Medical School, Harvard University, Boston, Massachusetts, USA.
Josh KorzenikCenter for Crohn's and Colitis, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Sonia FriedmanCenter for Crohn's and Colitis, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Beth Israel Deaconess Medical Center · USBrigham and Women's Hospital · USHarvard University · US

Funding

The Brown Initiative in HIV and AIDS Clinical Research for Minority CommunitiesR25MH083620 · NIMH · MIRIAM HOSPITAL · PI NUNN, AMY STEWART · 2008 to 2025
$3.7M
NIMHD NIH HHS L60 MD002421NIMH NIH HHS R25 MH083620
6 · The paper itself

Abstract

Background: Men with inflammatory bowel disease (IBD) may have increased sexual dysfunction. To measure the prevalence of sexual dysfunction in our male patients, we aimed to develop a new IBD-specific Male Sexual Dysfunction Scale (the IBD-MSDS). Methods: We used a cross-sectional survey and enrolled male patients (N = 175) ≥18 years old who attended IBD clinics at 2 Boston hospitals. We collected information on sexual functioning via a 15-item scale. General male sexual functioning was measured using the International Index of Erectile Dysfunction (IIEF); the Patient Health Questionnaire (PHQ-9) measured depressive symptoms. Medical history and sociodemographic information were extracted from medical record review. Exploratory factor analyses (EFA) assessed unidimensionality, factor structure, reliability, and criterion and construct validity of the 15-item scale. We used regression models to identify clinical factors associated with sexual dysfunction. Results: EFA suggested retaining 10-items generating a unidimensional scale with strong internal consistency reliability, α = 0.90. Criterion validity assessed using Spearman's coefficient showing that the IBD-MSDS was significantly correlated with all the subscales of the IIEF. The IBD-MSDS was significantly correlated (construct validity) with the PHQ-9 (P < 0.001) and the composite score for active IBD cases (P < 0.05). Male sexual dysfunction in IBD was significantly associated with the presence of an ileoanal pouch anastomosis (P = 0.047), depression (P < 0.001), and increased disease activity (P = 0.021). Conclusions: We have developed and validated an IBD-specific scale to assess the psychosexual impact of IBD. This new survey tool may help physicians screen for and identify factors contributing to impaired sexual functioning in their male patients.

Indexed as

AdultAgedAged, 80 and overBostonCross-Sectional StudiesDepressionErectile DysfunctionHumansInflammatory Bowel DiseasesMaleMiddle AgedProctocolectomy, RestorativePsychiatric Status Rating ScalesQuality of LifeRegression AnalysisReproducibility of ResultsCrohn’s diseaseinflammatory bowel diseasemensexual dysfunctionulcerative colitis

Identifiers

PMID29361102
PMCPMC6014620
OpenAlexW2070439874

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.