Evidence map›Paper›PMID 29360527›Full record

ArticleThe Journal of allergy and clinical immunology2018

Engineering and stable production of recombinant IgE for cancer immunotherapy and AllergoOncology.

Silvia Crescioli, Giulia Chiaruttini, Silvia Mele, Kristina M Ilieva, Giulia Pellizzari, Daniel I R Spencer, Richard A Gardner, Katie E Lacy, James F Spicer, Andrew N J Tutt and 2 more

Open access · hybridAbstract readLetter
In one paragraph

Article in The Journal of allergy and clinical immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 25 citations in OpenAlex.

  1. AllergoOncology in Review: Harnessing Allergy in the Field of Oncology to Improve Patient Outcomes.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. A versatile genomic transgenesis platform with enhancedFrontiers in bioengineering and biotechnology · 2023
    Article
  7. Generation and Characterization of Native and Sialic Acid-Deficient IgE.International journal of molecular sciences · 2022
    Article
  8. Review
  9. Oncoimmunology · 2021
    Article
  10. IgE Antibodies against Cancer: Efficacy and Safety.Antibodies (Basel, Switzerland) · 2020
    Review
  11. Filling the Antibody Pipeline in Allergy: PIPE Cloning of IgE, IgGInternational journal of molecular sciences · 2020
    Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. mAbs
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Silvia CrescioliSt John's Institute of Dermatology, School of Basic & Medical Biosciences, King's College London, London, United Kingdom; NIHR Biomedical Research Centre at Guy's and St Thomas's Hospitals and King's College London, London, United Kingdom.
Giulia ChiaruttiniSt John's Institute of Dermatology, School of Basic & Medical Biosciences, King's College London, London, United Kingdom.
Silvia MeleSt John's Institute of Dermatology, School of Basic & Medical Biosciences, King's College London, London, United Kingdom.
Kristina M IlievaSt John's Institute of Dermatology, School of Basic & Medical Biosciences, King's College London, London, United Kingdom; Breast Cancer Now Unit, School of Cancer & Pharmaceutical Sciences, King's College London, Guy's Cancer Centre, London, United Kingdom.
Giulia PellizzariSt John's Institute of Dermatology, School of Basic & Medical Biosciences, King's College London, London, United Kingdom.
Daniel I R SpencerLudger, Culham Science Centre, Abingdon, United Kingdom.
Richard A GardnerLudger, Culham Science Centre, Abingdon, United Kingdom.
Katie E LacySt John's Institute of Dermatology, School of Basic & Medical Biosciences, King's College London, London, United Kingdom.
James F SpicerSchool of Cancer & Pharmaceutical Sciences, King's College London, Guy's Hospital, London, United Kingdom.
Andrew N J TuttBreast Cancer Now Unit, School of Cancer & Pharmaceutical Sciences, King's College London, Guy's Cancer Centre, London, United Kingdom; Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, London, United Kingdom.
Gerd K WagnerDepartment of Chemistry, Faculty of Natural & Mathematical Sciences, King's College London, London, United Kingdom.
Sophia N KaragiannisSt John's Institute of Dermatology, School of Basic & Medical Biosciences, King's College London, London, United Kingdom; NIHR Biomedical Research Centre at Guy's and St Thomas's Hospitals and King's College London, London, United Kingdom; Breast Cancer Now Unit, School of Cancer & Pharmaceutical Sciences, King's College London, Guy's Cancer Centre, London, United Kingdom. Electronic address: sophia.karagiannis@kcl.ac.uk.
King's College London · GBCulham Science Centre · GBSt Thomas' Hospital · GBGuy's Hospital · GBInstitute of Cancer Research · GB

Funding

Biotechnology and Biological Sciences Research Council IBCARB-POC-0616-040Cancer Research UK C1519/A10331Cancer Research UK C30122/A11527Cancer Research UK C30122/A157745Department of HealthMedical Research Council MR/L023091/1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AllergensAntibodiesAntigens, NeoplasmCell LineCell Line, TumorHEK293 CellsHumansHypersensitivityImmunoglobulin EImmunotherapyMembrane ProteinsNeoplasmsRecombinant ProteinsAllergensAntibodiesAntigens, NeoplasmImmunoglobulin EMembrane ProteinsRecombinant Proteins

Identifiers

PMID29360527
PMCPMC6286379
OpenAlexW2782689229

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.