Evidence map›Paper›PMID 29360429›Full record

ArticleThe Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases

Retrospective evaluation of the clinical characteristics associated with Corynebacterium species bacteremia.

Mitsuru Yanai, Maiko Ogasawasa, Yuta Hayashi, Kiyozumi Suzuki, Hiromichi Takahashi, Atsushi Satomura

Abstract read
In one paragraph

Article in The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. True infection or contamination in patients with positive Cutibacterium blood cultures-a retrospective cohort study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2022
    Article
  5. Article
  6. Review
  7. BMJ case reports · 2021
    Article
  8. Molecular and clinical oncology · 2021
    Article
  9. Clinical characteristics and drug susceptibility patterns of Corynebacterium species in bacteremic patients with hematological disorders.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021
    Article
  10. Access microbiology · 2021
    Article
  11. Article
  12. From contamination to infective endocarditis-a population-based retrospective study of Corynebacterium isolated from blood cultures.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020
    Article
  13. Article
  14. Article
  15. Central venous catheter-related infections caused by Corynebacterium amycolatum and other multiresistant non-diphtherial corynebacteria in paediatric oncology patients.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mitsuru YanaiNihon University School of Medicine, Department of Internal Medicine, Division of General Medicine, Tokyo, Japan. Electronic address: yanai.mitsuru@nihon-u.ac.jp.
Maiko OgasawasaNihon University School of Medicine, Department of Internal Medicine, Division of General Medicine, Tokyo, Japan.
Yuta HayashiNihon University School of Medicine, Department of Internal Medicine, Division of General Medicine, Tokyo, Japan.
Kiyozumi SuzukiNihon University School of Medicine, Department of Internal Medicine, Division of General Medicine, Tokyo, Japan.
Hiromichi TakahashiNihon University School of Medicine, Department of Pathology and Mircobiology, Division of Laboratory Medicine, Tokyo, Japan.
Atsushi SatomuraNihon University School of Medicine, Department of Pathology and Mircobiology, Division of Laboratory Medicine, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesCorynebacterium spp. are becoming recognized as pathogens that potentially cause various infections. We aimed to evaluate the clinical characteristics associated with Corynebacterium spp. bacteremia. PATIENTS AND

methodsWe retrospectively reviewed the medical records of all adult patients who had positive blood cultures for Corynebacterium spp. in a single university hospital between January 2014 and December 2016. Patients were divided into a bacteremia group and a contamination group based on microbiological test results and clinical characteristics. Patients' characteristics, antimicrobial susceptibility of isolated species, antimicrobials administered, and patient outcomes were evaluated.

resultsCorynebacterium spp. were isolated from blood samples of 63 patients; Corynebacterium striatum was the predominant isolate. Twenty-eight patients were determined to have bacteremia. Younger age (p=0.023), shorter time to positivity (p=0.006), longer hospital stay (p=0.009), and presence of an indwelling vascular catheter (p=0.002) were observed more often in the bacteremia group compared to the contamination group. The source of infection in most patients with bacteremia was an intravenous catheter. All tested strains were susceptible to vancomycin. Four of the 27 patients with bacteremia died, despite administration of appropriate antimicrobial therapy.

conclusionsWe found that younger age, shorter time to positivity, and presence of an indwelling catheter were related to bacteremia caused by Corynebacterium spp. Appropriate antimicrobials should be administered once Corynebacterium spp. are isolated from the blood and bacteremia is suspected.

Indexed as

AgedAged, 80 and overAge FactorsAnti-Bacterial AgentsBacteremiaBlood CultureCorynebacteriumCorynebacterium InfectionsDrug Resistance, Multiple, BacterialFemaleHospitals, UniversityHumansMaleMedical RecordsMicrobial Sensitivity TestsMiddle AgedAnti-Bacterial AgentsBlood cultureBloodstream infectionContaminationCorynebacterium species

Identifiers

PMID29360429
PMCPMC9425686

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.