Evidence map›Paper›PMID 29360168›Full record

ArticleSynapse (New York, N.Y.)2018

Activity-dependent plasticity of presynaptic GABA

Adeline Orts-Del'Immagine, Jason R Pugh

Abstract read
In one paragraph

Article in Synapse (New York, N.Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Co-release of GABA and ACh from Medial Olivocochlear Neurons as a Fine Regulatory Mechanism of Cochlear Efferent Inhibition.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. GABACurrent neuropharmacology · 2022
    Review
  6. CaInternational journal of molecular sciences · 2022
    Review
  7. Keeping the Balance: GABABrain sciences · 2022
    Review
  8. Article
  9. Review
  10. Article
  11. Direction of action of presynaptic GABAJournal of neurophysiology · 2019
    Article
  12. Complex formation of APP with GABANature communications · 2019
    Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Adeline Orts-Del'ImmagineDepartment of Cellular and Integrative Physiology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78229.
Jason R PughDepartment of Cellular and Integrative Physiology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78229.ORCID 0000-0001-9042-7849
The University of Texas Health Science Center at San Antonio · US

Funding

Modulation of synaptic transmission by coactivation of presynaptic GABAA and GABAB receptors: kinetics, plasticity, and functional consequencesR01NS092809 · NINDS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI PUGH, JASON RICHARD · 2015 to 2019
$1.6M
NINDS NIH HHS R01 NS092809
6 · The paper itself

Abstract

Parallel fiber synapses in the cerebellum express a wide range of presynaptic receptors. However, presynaptic receptor expression at individual parallel fiber synapses is quite heterogeneous, suggesting physiological mechanisms regulate presynaptic receptor expression. We investigated changes in presynaptic GABA

Indexed as

Action PotentialsAnimalsAnimals, NewbornBiophysicsCalciumCerebellumElectric StimulationFemaleGABA AgentsIn Vitro TechniquesMaleMiceNerve FibersPatch-Clamp TechniquesReceptors, GABA-BReceptors, PresynapticCalciumGABA AgentsReceptors, GABA-BReceptors, PresynapticcerebellumGABABparallel fiberplasticitypresynapticstellatesynapse

Identifiers

PMID29360168
PMCPMC6003616
OpenAlexW2793516707

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.