Evidence map›Paper›PMID 29359806›Full record

ReviewThe Journal of physiology2018

The role of hypoxia-inducible factors in carotid body (patho) physiology.

Gregg L Semenza, Nanduri R Prabhakar

Open access · bronzeAbstract readReview
In one paragraph

Review in The Journal of physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 80 citations in OpenAlex.

  1. Rapid eye movement-related obstructive sleep apnea: a physiological phenotype predicting favorable outcomes following palatal surgery.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  2. Function ofInsects · 2026
    Article
  3. Sleep, Neural Circulatory Control, and Cardiovascular Disease: A Mechanistic Review.Arteriosclerosis, thrombosis, and vascular biology · 2026
    Review
  4. Nocturnal Hypoxaemia in PAH Patients Living at High Altitude Relocated to Low Altitude.Respiration; international review of thoracic diseases · 2026
    Article
  5. Article
  6. Review
  7. Review
  8. Hif-2α programs oxygen chemosensitivity in chromaffin cells.The Journal of clinical investigation · 2024
    Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Three Days of Chronic Intermittent Hypoxia Induce βAdvances in experimental medicine and biology · 2023
    Article
  16. Review
  17. Article
  18. Coronavirus Disease 2019 and Takotsubo Syndrome.Reviews in cardiovascular medicine · 2022
    Review
  19. The effect of HIF on metabolism and immunity.Nature reviews. Nephrology · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Gregg L SemenzaInstitute for Cell Engineering, McKusick-Nathans Institute of Genetic Medicine, and Departments of Pediatrics, Medicine, Oncology, Radiation Oncology, and Biological Chemistry, the Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0000-0002-0913-211X
Nanduri R PrabhakarInstitute for Integrative Physiology and Center for Systems Biology of O2 Sensing, Biological Sciences Division, University of Chicago, Chicago, IL, USA.ORCID 0000-0003-4570-1380
Johns Hopkins University · USUniversity of Chicago · US

Funding

Integrative Consequences of HypoxiaP01HL090554 · NHLBI · UNIVERSITY OF CHICAGO · PI PRABHAKAR, NANDURI R · 2008 to 2017
$21.4M
Mechanisms Underlying Sympathetic Activation-dependent Endothelial Cell Activation by Chronic Intermittent HypoxiaP01HL144454 · NHLBI · UNIVERSITY OF CHICAGO · PI PRABHAKAR, NANDURI R · 2019 to 2023
$12.7M
NHLBI NIH HHS P01 HL144454NHLBI NIH HHS PO1-HL-90554
6 · The paper itself

Abstract

Hypoxia-inducible factors mediate adaptive responses to reduced O

Indexed as

AnimalsBasic Helix-Loop-Helix ProteinsCarotid BodyHumansHypertensionHypoxiaOxygenSleep Apnea SyndromesBasic Helix-Loop-Helix ProteinsOxygenHIF-1HIF-2NADPH oxidaseRedox Statesleep apneaSuperoxide dismutase

Identifiers

PMID29359806
PMCPMC6068252
OpenAlexW2797768512

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.