Evidence map›Paper›PMID 29359762›Full record

ArticleNature chemistry2018

DNA-imprinted polymer nanoparticles with monodispersity and prescribed DNA-strand patterns.

Tuan Trinh, Chenyi Liao, Violeta Toader, Maciej Barłóg, Hassan S Bazzi, Jianing Li, Hanadi F Sleiman

Abstract read
PubMed Publisher
In one paragraph

Article in Nature chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Exploring Size-Controlled Exciton Evolution Using DNA Libraries.Journal of the American Chemical Society · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Nano-Bio Interactions between DNA Nanocages and Human Serum Albumin.Journal of chemical theory and computation · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Chemically modified DNA nanostructures for drug delivery.Innovation (Cambridge (Mass.)) · 2022
    Review
  15. Review
  16. Functional DNA-Polymer Conjugates.Chemical reviews · 2021
    Review
  17. Rationally Programming Nanomaterials with DNA for Biomedical Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Review
  18. DNA Transformations for Diagnosis and Therapy.Advanced functional materials · 2021
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tuan TrinhDepartment of Chemistry and Center for Self-Assembled Chemical Structures, McGill University, 801 Sherbrooke Street West, Montreal, Quebec H3A 0B8, Canada.
Chenyi LiaoDepartment of Chemistry, The University of Vermont, Burlington, VT 05405, USA.
Violeta ToaderDepartment of Chemistry and Center for Self-Assembled Chemical Structures, McGill University, 801 Sherbrooke Street West, Montreal, Quebec H3A 0B8, Canada.
Maciej BarłógDepartment of Chemistry, Texas A&M University at Qatar, P.O. Box 23874, Doha, Qatar.
Hassan S BazziDepartment of Chemistry, Texas A&M University at Qatar, P.O. Box 23874, Doha, Qatar.
Jianing LiDepartment of Chemistry, The University of Vermont, Burlington, VT 05405, USA.ORCID 0000-0002-0143-8894
Hanadi F SleimanDepartment of Chemistry and Center for Self-Assembled Chemical Structures, McGill University, 801 Sherbrooke Street West, Montreal, Quebec H3A 0B8, Canada.ORCID 0000-0002-5100-0532

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As colloidal self-assembly increasingly approaches the complexity of natural systems, an ongoing challenge is to generate non-centrosymmetric structures. For example, patchy, Janus or living crystallization particles have significantly advanced the area of polymer assembly. It has remained difficult, however, to devise polymer particles that associate in a directional manner, with controlled valency and recognition motifs. Here, we present a method to transfer DNA patterns from a DNA cage to a polymeric nanoparticle encapsulated inside the cage in three dimensions. The resulting DNA-imprinted particles (DIPs), which are 'moulded' on the inside of the DNA cage, consist of a monodisperse crosslinked polymer core with a predetermined pattern of different DNA strands covalently 'printed' on their exterior, and further assemble with programmability and directionality. The number, orientation and sequence of DNA strands grafted onto the polymeric core can be controlled during the process, and the strands are addressable independently of each other.

Indexed as

Molecular ImprintingDNAMolecular StructureNanoparticlesParticle SizePolymersDNAPolymers

Identifiers

PMID29359762

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.