ArticleNature chemistry2018
Iridium-catalysed arylation of C-H bonds enabled by oxidatively induced reductive elimination.
Article in Nature chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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Who cites it
19 citing papers in PubMed.
- Controlling Reductive Elimination Pathways in Ti(IV) Pincer Complexes: Concerted versus Radical Mechanisms via Ligand Design.Journal of the American Chemical Society · 2026Article
- Persistent acyclic Cp*Ir(III) complexes and their reactivities in cross-coupling reactions.Nature communications · 2025Article
- Unlocking Catalysis Using Oxidatively Induced Reductive Elimination.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Review
- Oxidatively-induced C(spChemical science · 2024Article
- The crucial role of silver(I)-salts as additives in C-H activation reactions: overall analysis of their versatility and applicability.Chemical Society reviews · 2023Review
- Visible-Light-Induced, Single-Metal-Catalyzed, Directed C-H Functionalization: Metal-Substrate-Bound Complexes as Light-Harvesting Agents.Angewandte Chemie (International ed. in English) · 2022Review
- OvercomingChemical science · 2022Article
- Article
- Review
- Unconventional mechanism and selectivity of the Pd-catalyzed C-H bond lactonization in aromatic carboxylic acid.Nature communications · 2022Article
- Atropo-Enantioselective Oxidation-Enabled Iridium(III)-Catalyzed C-H Arylations with Aryl Boronic Esters.Angewandte Chemie (International ed. in English) · 2021Article
- Organic Electrochemistry: Molecular Syntheses with Potential.ACS central science · 2021Review
- Ruthenaelectro-Catalyzed Domino Three-Component Alkyne Annulation for Expedient Isoquinoline Assembly.Angewandte Chemie (International ed. in English) · 2021Article
- Facilitating Ir-Catalyzed C-H Alkynylation with Electrochemistry: Anodic Oxidation-Induced Reductive Elimination.ACS catalysis · 2020Article
- Lewis acid-assisted Ir(iii) reductive elimination enables construction of seven-membered-ring sulfoxides.Chemical science · 2020Article
- Azaruthena(II)-bicyclo[3.2.0]heptadiene: Key Intermediate for Ruthenaelectro(II/III/I)-catalyzed Alkyne Annulations.Angewandte Chemie (International ed. in English) · 2020Article
- Insights into Cobalta(III/IV/II)-Electrocatalysis: Oxidation-Induced Reductive Elimination for Twofold C-H Activation.Angewandte Chemie (International ed. in English) · 2020Article
- Revealing the Iron-Catalyzed β-Methyl Scission ofMolecules (Basel, Switzerland) · 2020Article
- Ag/Pd Cocatalyzed Direct Arylation of Fluoroarene Derivatives with Aryl Bromides.ACS catalysis · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Direct arylation of C-H bonds is in principle a powerful way of preparing value-added molecules that contain carbon-aryl fragments. Unfortunately, currently available synthetic methods are not sufficiently effective to be practical alternatives to conventional cross-coupling reactions. We propose that the main problem lies in the late portion of the catalytic cycle where reductive elimination gives the desired carbon-aryl bond. Accordingly, we have developed a strategy where the Ir(III) centre of the key intermediate is first oxidized to Ir(IV). Density functional theory calculations indicate that the barrier to reductive elimination is reduced by nearly 19 kcal mol
Identifiers
29359741What OpenQuestion holds
Registered trials
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