Evidence map›Paper›PMID 29359271›Full record

ReviewJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2018

Molecular imaging of calcific aortic valve disease.

Jae-Joon Jung, Farid Jadbabaie, Mehran M Sadeghi

Open access · greenAbstract readReview
In one paragraph

Review in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jae-Joon JungCardiovascular Molecular Imaging Laboratory, Section of Cardiovascular Medicine and Yale Cardiovascular Research Center, Yale School of Medicine, New Haven, USA.
Farid JadbabaieCardiovascular Molecular Imaging Laboratory, Section of Cardiovascular Medicine and Yale Cardiovascular Research Center, Yale School of Medicine, New Haven, USA.
Mehran M SadeghiCardiovascular Molecular Imaging Laboratory, Section of Cardiovascular Medicine and Yale Cardiovascular Research Center, Yale School of Medicine, New Haven, USA. mehran.sadeghi@yale.edu.
VA Connecticut Healthcare System · USYale University · US

Funding

Novel Regulators of Calcific Aortic Valve DiseaseR01HL138567 · NHLBI · YALE UNIVERSITY · PI SADEGHI, MEHRAN M · 2017 to 2020
$2.8M
Imaging protease activation in calcific aortic valve diseaseR01HL114703 · NHLBI · YALE UNIVERSITY · PI SADEGHI, MEHRAN M · 2012 to 2016
$2.0M
Molecular Imaging of Protease Activation in AneurysmI01BX001750 · VA · VA CONNECTICUT HEALTHCARE SYSTEM · PI SADEGHI, MEHRAN M · 2013 to 2016
–
BLRD VA I01 BX001750NHLBI NIH HHS R01 HL114703NHLBI NIH HHS R01 HL138567
6 · The paper itself

Abstract

Calcific aortic valve disease (CAVD) can progress to symptomatic aortic stenosis in a subset of patients. The severity of aortic stenosis and the extent of valvular calcification can be evaluated readily by echocardiography, CT, and MRI using well-established imaging protocols. However, these techniques fail to address optimally other important aspects of CAVD, including the propensity for disease progression, risk of complications in asymptomatic patients, and the effect of therapeutic interventions on valvular biology. These gaps may be addressed by molecular imaging targeted at key biological processes such as inflammation, remodeling, and calcification that mediate the development and progression of CAVD. In this review, recent advances in valvular molecular imaging, including

Indexed as

AnimalsAortic ValveAortic Valve StenosisCalcinosisFluorodeoxyglucose F18HumansMiceMolecular ImagingPositron-Emission TomographyTomography, Emission-Computed, Single-PhotonFluorodeoxyglucose F18Aortic stenosisaortic valveFDGmatrix metalloproteinasesmolecular imagingsodium fluoride

Identifiers

PMID29359271
PMCPMC6054901
OpenAlexW2790599314

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.