ReviewDevelopment & reproduction2017
A Review of Mechanisms of Implantation.
Review in Development & reproduction, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 141 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
141 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Effects of autologous platelet-rich plasma in recurrent implantation failure: a systematic review and meta-analysis.Frontiers in endocrinology · 2026Pooled it
- Exploring the presence of markers of decidualization in the fallopian tubes: a systematic review.Biology of reproduction · 2023Pooled it
- Impact of Physical Activity and Sedentary Behavior on Spontaneous Female and Male Fertility: A Systematic Review.Journal of physical activity & health · 2023Pooled it
- Growth Hormone Administration to Improve Reproductive Outcomes in Women with Recurrent Implantation Failure (RIF): a Systematic Review.Reproductive sciences (Thousand Oaks, Calif.) · 2023Pooled it
- Development of placental abnormalities in location and anatomy.Acta obstetricia et gynecologica Scandinavica · 2020Pooled it
- Assessing the efficacy and safety of SildenafilJournal of medicine and life · 2023Trial
- Growth Hormone: A Potential Treatment of Patients with Refractory Thin Endometrium: A Clinical Trial Study.International journal of fertility & sterility · 2022Trial
- Association of GPR30 Genetic Variants with Recurrent Implantation Failure: A Case-Control Study Comparing Fertile Women, ART Success and RIF Patients.Reproductive sciences (Thousand Oaks, Calif.) · 2026Article
- Exploring Spatial Patterning of Endothelial Cells and Trophoblast Cells in a Microfluidic Device.Tissue engineering. Part A · 2026Article
- Therapeutic Potential of Mesenchymal Stem Cells in Multiple Sclerosis: An Updated Review.Molecular neurobiology · 2026Review
- Review
- What is pregnancy and what is disease? a critique of Smajdor and Räsänen's "is pregnancy a disease? a normative approach".Monash bioethics review · 2026Article
- The Positive Roles for Reactive Oxygen Species in Human Reproduction; Implications for the Therapeutic Application of Antioxidants.Antioxidants (Basel, Switzerland) · 2026Review
- Gestational fine particulate matter exposure and perinatal outcomes in the ECHO cohort: Associations across pregnancy windows.Environmental research · 2026Article
- Bushen Huoxue recipe regulates endometrial epithelial ion channels to promote embryo implantation in controlled ovarian hyperstimulation mice.Journal of the Chinese Medical Association : JCMA · 2026Article
- Anthocyanin Enhances Development, Hatching, and GLUT4 Expression in In Vitro-Cultured ICR Mouse Blastocysts.Life (Basel, Switzerland) · 2026Article
- Modelling mammalian implantationAnimal reproduction · 2026Review
- Microfluidic On-Chip Assay for Quantifying Blastoid Adhesion to Endometrial Epithelium.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Novel injectable sodium alginate hydrogel developed for improved endometrial repair with human umbilical cord mesenchymal stem cells.Drug delivery and translational research · 2025Article
- Implantation Failure: Where to Look Up?Journal of clinical medicine · 2025Review
81 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Implantation is a highly organized process that involves an interaction between a receptive uterus and a competent blastocyst. In humans, natural fecundity suggests that the chance of conception per cycle is relatively low (~30%) and two-third of lost pregnancies occur because of implantation failure. Defective implantation leads to adverse pregnancy outcomes including infertility, spontaneous miscarriage, intrauterine fetal growth restriction and preeclampsia. With use of advanced scientific technologies, gene expression analysis and genetically-engineered animal models have revealed critical cellular networks and molecular pathways. But, because of ethical restrictions and the lack of a mechanistic experiment, comprehensive steps in human implantation have still not been completely understood. This review primarily focuses on the recent advances in mechanisms of implantation. Because infertility is an emerging issue these days, gaining an understanding the molecular and hormonal signaling pathway will improve the outcome of natural pregnancy and assisted reproductive technology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.