Evidence map›Paper›PMID 29359188›Full record

ArticlemSphere

Identification of Head and Neck Cancer Subtypes Based on Human Papillomavirus Presence and E2F-Regulated Gene Expression.

Molly E Johnson, Paul G Cantalupo, James M Pipas

Abstract read
In one paragraph

Article in mSphere. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
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  6. Review
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  16. The Oncogenic Roles ofDiagnostics (Basel, Switzerland) · 2020
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Molly E JohnsonDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Paul G CantalupoDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
James M PipasDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

Funding

Searching Environmental Metagenomes for Novel Infectious Cancer Agents (PQ12)R21CA170248 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PIPAS, JAMES M · 2012 to 2013
$355k
NCI NIH HHS R21 CA170248
6 · The paper itself

Abstract

Human papillomavirus (HPV) is present in a subset of head and neck squamous cell carcinomas (HNSCCs). The cell cycle regulatory Rb-E2F pathway is a major target of HPV and is perturbed by these viruses in cell culture and animal models, as well as in human tumors. In this study, we examined differences in the Rb-E2F pathway displayed by HPV-positive (HPV

Indexed as

cancerHPVmetagenomicstumor suppressor genes

Identifiers

PMID29359188
PMCPMC5760753

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.