ArticleTranslational vision science & technology2018
The Interrelationship between Refractive Error, Blood Vessel Anatomy, and Glaucomatous Visual Field Loss.
Article in Translational vision science & technology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 15 citations in OpenAlex.
- Retinal Vessel Automatic Segmentation Using SegNet.Computational and mathematical methods in medicine · 2022Article
- Towards Automated Eye Diagnosis: An Improved Retinal Vessel Segmentation Framework Using Ensemble Block Matching 3D Filter.Diagnostics (Basel, Switzerland) · 2021Article
- Change of Retinal Vessels in Different Sectors of the Parapapillary Area in Primary Open-Angle Glaucoma.Frontiers in medicine · 2021Article
- Inter-Eye Association of Visual Field Defects in Glaucoma and Its Clinical Utility.Translational vision science & technology · 2020Article
- An Artificial Intelligence Approach to Assess Spatial Patterns of Retinal Nerve Fiber Layer Thickness Maps in Glaucoma.Translational vision science & technology · 2020Article
- Sex-Specific Differences in Circumpapillary Retinal Nerve Fiber Layer Thickness.Ophthalmology · 2020Article
- Compensation of retinal nerve fibre layer thickness as assessed using optical coherence tomography based on anatomical confounders.The British journal of ophthalmology · 2020Article
- Ametropia, retinal anatomy, and OCT abnormality patterns in glaucoma. 1. Impacts of refractive error and interartery angle.Journal of biomedical optics · 2017Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
Abstract
purposeWe quantified the interrelationship between retinal blood vessel (BV) anatomical variation, spherical equivalent (SE) of refractive error, and functional diagnostic parameters in glaucoma to identify optimal parameters for the improvement of optical coherence tomography (OCT) retinal nerve fiber layer thickness (RNFLT) norms.
methodsA trained observer marked the intersections of the main superior/inferior temporal arteries and veins with concentric circles around the optic nerve head (ONH) center on fundus images. The interrelationship of BV, SE, and visual field global parameters was analyzed by multivariate regression and model comparison.
resultsA total of 445 eyes of 445 patients in a large glaucoma practice were selected. Of all investigated BV parameters, interartery angles (IAA) between superior and inferior arteries at a radius of 1.73 mm around the ONH center demonstrated the strongest relationship to SE (Bayesian information criterion difference to null model, 11.9). SE and BV parameters are unrelated to functional parameters, including mean deviation (MD), pattern standard deviation, and glaucoma hemifield test results.
conclusionsBV locations outside the ONH are sufficiently stable over glaucoma severity to represent individual eye anatomy, and the IAA at 1.73 mm eccentricity is the optimal parameter to be considered for novel OCT RNFLT norms. TRANSLATIONAL RELEVANCE: Among a large set of BV location parameters, considering IAA may improve RNFLT norms optimally and thereby increase the accuracy of clinical glaucoma diagnosis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.