Evidence map›Paper›PMID 29359106›Full record

ArticleBiomedical optics express2018

Compact, multi-exposure speckle contrast optical spectroscopy (SCOS) device for measuring deep tissue blood flow.

Tanja Dragojević, Joseph L Hollmann, Davide Tamborini, Davide Portaluppi, Mauro Buttafava, Joseph P Culver, Federica Villa, Turgut Durduran

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 69 citations in OpenAlex.

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  15. Wide-field intensity fluctuation imaging.Biomedical optics express · 2024
    Article
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  20. Wide-field Intensity Fluctuation Imaging.bioRxiv : the preprint server for biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Tanja DragojevićICFO-Institut de Ciències Fotòniques, The Barcelona Institute of Science and Technology, Av. Carl Friedrich Gauss, 3, Castelldefels (Barcelona), 08860, Spain.
Joseph L HollmannICFO-Institut de Ciències Fotòniques, The Barcelona Institute of Science and Technology, Av. Carl Friedrich Gauss, 3, Castelldefels (Barcelona), 08860, Spain.
Davide TamboriniPolitecnico di Milano, Dipartimento di Elettronica, Informatione e Bioingegneria, Piazza Leonardo Da Vinci 32, Milan, 20133, Italy.
Davide PortaluppiPolitecnico di Milano, Dipartimento di Elettronica, Informatione e Bioingegneria, Piazza Leonardo Da Vinci 32, Milan, 20133, Italy.
Mauro ButtafavaPolitecnico di Milano, Dipartimento di Elettronica, Informatione e Bioingegneria, Piazza Leonardo Da Vinci 32, Milan, 20133, Italy.
Joseph P CulverDepartment of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Federica VillaPolitecnico di Milano, Dipartimento di Elettronica, Informatione e Bioingegneria, Piazza Leonardo Da Vinci 32, Milan, 20133, Italy.
Turgut DurduranICFO-Institut de Ciències Fotòniques, The Barcelona Institute of Science and Technology, Av. Carl Friedrich Gauss, 3, Castelldefels (Barcelona), 08860, Spain.
Politecnico di Milano · ITInstitute of Photonic Sciences · ESInstitució Catalana de Recerca i Estudis Avançats · ESWashington University in St. Louis · US

Funding

High-Sensitivity DOT for Mapping Human Brain FunctionR01NS090874 · NINDS · WASHINGTON UNIVERSITY · PI CULVER, JOSEPH P · 2014 to 2025
$5.5M
MAPPING FUNCTIONAL CONNECTIVITY WITH FLUORESCENCE MOLECULAR TOMOGRAPHYR01NS099429 · NINDS · WASHINGTON UNIVERSITY · PI CULVER, JOSEPH P · 2017 to 2021
$2.9M
OPTICAL IMAGING AND FUNCTIONAL CONNECTIVITY MAPPING FOR MICER01NS078223 · NINDS · WASHINGTON UNIVERSITY · PI CULVER, JOSEPH P · 2012 to 2016
$2.7M
NINDS NIH HHS R01 NS078223NINDS NIH HHS R01 NS090874NINDS NIH HHS R01 NS099429
6 · The paper itself

Abstract

Speckle contrast optical spectroscopy (SCOS) measures absolute blood flow in deep tissue, by taking advantage of multi-distance (previously reported in the literature) or multi-exposure (reported here) approach. This method promises to use inexpensive detectors to obtain good signal-to-noise ratio, but it has not yet been implemented in a suitable manner for a mass production. Here we present a new, compact, low power consumption, 32 by 2 single photon avalanche diode (SPAD) array that has no readout noise, low dead time and has high sensitivity in low light conditions, such as

Indexed as

(170.0170) Medical optics and biotechnology(170.1470) Blood or tissue constituent monitoring(170.3890) Medical optics instrumentation(300.6480) Spectroscopy, speckle

Identifiers

PMID29359106
PMCPMC5772585
OpenAlexW2779158431

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.