ArticleBiomedical optics express2018
Quantization of collagen organization in the stroma with a new order coefficient.
Article in Biomedical optics express, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 16 citations in OpenAlex.
- Biomechanical changes and associated factors of preserved SMILE-derived corneal stromal lenticules.Eye (London, England) · 2026Article
- Second-harmonic generation microscopy of murine scleral remodeling by collagenase and reparative collagen mimetic peptides.Frontiers in medicine · 2025Article
- A review of the epithelial and stromal effects of corneal collagen crosslinking.The ocular surface · 2023Review
- Estimation of scleral mechanical properties from air-puff optical coherence tomography.Biomedical optics express · 2021Article
- Three-dimensional collagen fiber mapping and tractography of human uterine tissue using OCT.Biomedical optics express · 2020Article
- Corneal Collagen Ordering After In Vivo Rose Bengal and Riboflavin Cross-Linking.Investigative ophthalmology & visual science · 2020Article
- High-speed collagen fiber modeling and orientation quantification for optical coherence tomography imaging.Optics express · 2019Article
- Quantitative Discrimination of Healthy and Diseased Corneas With Second Harmonic Generation Microscopy.Translational vision science & technology · 2019Article
- Quantitative Analysis of the Corneal Collagen Distribution afterBioMed research international · 2019Article
- Correlations between corneal biomechanics and specular microscopy in patient with cataract.Romanian journal of ophthalmologyObservational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many optical and biomechanical properties of the cornea, specifically the transparency of the stroma and its stiffness, can be traced to the degree of order and direction of the constituent collagen fibers. To measure the degree of order inside the cornea, a new metric, the order coefficient, was introduced to quantify the organization of the collagen fibers from images of the stroma produced with a custom-developed second harmonic generation microscope. The order coefficient method gave a quantitative assessment of the differences in stromal collagen arrangement across the cornea depths and between untreated stroma and cross-linked stroma.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.