Evidence map›Paper›PMID 29358941›Full record

ReviewFrontiers in immunology2017

Methods of Controlling Invasive Fungal Infections Using CD8

Pappanaicken R Kumaresan, Thiago Aparecido da Silva, Dimitrios P Kontoyiannis

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. CAR-T therapy: Advances in respiratory diseases.Chinese medical journal pulmonary and critical care medicine · 2025
    Review
  5. Article
  6. mSphere · 2025
    Article
  7. Immunoengineering: An Emerging Field in Infectious Diseases.The Journal of infectious diseases · 2025
    Review
  8. Review
  9. Review
  10. Article
  11. Interplay of Cytokines and Chemokines in Aspergillosis.Journal of fungi (Basel, Switzerland) · 2024
    Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Pappanaicken R KumaresanDepartment of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Thiago Aparecido da SilvaDepartment of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Dimitrios P KontoyiannisDepartment of Infectious Diseases, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.

Funding

PR1-specific CB T cells for Patients with Myeloid MalignanciesP01CA148600 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI MOLLDREM, JEFFREY J · 2011 to 2022
$24.4M
Redirected T Cell Therapy to Cure Invasive Fungal InfectionsR33AI127381 · NIAID · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI KONTOYIANNIS, DIMITRIOS P, KUMAR, PAPPANAICKEN RANGASAMY · 2019 to 2021
$1.4M
UCB-DERIVED CD19-SPECIFIC T CELLS FOR UNIVERSAL TREATMENT OF B-CELL MALIGNANCYR33CA116127 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI COOPER, LAURENCE J.N. · 2010 to 2011
$1.4M
Redirected T Cell Therapy to Cure Invasive Fungal InfectionsR21AI127381 · NIAID · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI KONTOYIANNIS, DIMITRIOS P, KUMAR, PAPPANAICKEN RANGASAMY · 2017 to 2018
$436k
UCB-DERIVED CD19-SPECIFIC T CELLS FOR UNIVERSAL TREATMENT OF B-CELL MALIGNANCYR21CA116127 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI COOPER, LAURENCE J.N. · 2007 to 2008
$371k
NCI NIH HHS P01 CA148600NCI NIH HHS R21 CA116127NCI NIH HHS R33 CA116127NIAID NIH HHS R21 AI127381NIAID NIH HHS R33 AI127381
6 · The paper itself

Abstract

Invasive fungal infections (IFIs) cause high rates of morbidity and mortality in immunocompromised patients. Pattern-recognition receptors present on the surfaces of innate immune cells recognize fungal pathogens and activate the first line of defense against fungal infection. The second line of defense is the adaptive immune system which involves mainly CD4

Indexed as

adoptive T cell therapyCD8+ T cellscell therapychimeric antigen receptorD-CAR+ T cellsfungal infectionimmunotherapySleeping Beauty

Identifiers

PMID29358941
PMCPMC5766637

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.