Evidence map›Paper›PMID 29358898›Full record

ArticleJournal of the Royal Statistical Society. Series B, Statistical methodology2017

Concordance-Assisted Learning for Estimating Optimal Individualized Treatment Regimes.

Caiyun Fan, Wenbin Lu, Rui Song, Yong Zhou

Abstract read
In one paragraph

Article in Journal of the Royal Statistical Society. Series B, Statistical methodology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Semiparametric regression modeling of the global percentile outcome.Journal of statistical planning and inference · 2023
    Article
  4. Article
  5. Article
  6. Statistical Inference for Online Decision-Making: In a Contextual Bandit Setting.Journal of the American Statistical Association · 2021
    Article
  7. Article
  8. Article
  9. Maximin Projection Learning for Optimal Treatment Decision with Heterogeneous Individualized Treatment Effects.Journal of the Royal Statistical Society. Series B, Statistical methodology · 2018
    Article
  10. Article
  11. Sparse concordance-assisted learning for optimal treatment decision.Journal of machine learning research : JMLR · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Caiyun FanSchool of Business Information, Shanghai University of International Business and Economics Shanghai 201620, China.
Wenbin LuDepartment of Statistics, North Carolina State University Raleigh, NC 27695, U.S.A.
Rui SongDepartment of Statistics, North Carolina State University Raleigh, NC 27695, U.S.A.
Yong ZhouSchool of Statistics and Management, Shanghai University of Finance and Economics Shanghai 200433, China.

Funding

Statistical Methods for Cancer Clinical TrialsP01CA142538 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVIDIAN, MARIE, KOSOROK, MICHAEL R · 2010 to 2019
$21.3M
NCI NIH HHS P01 CA142538
6 · The paper itself

Abstract

In this article, we propose a new concordance-assisted learning for estimating optimal individualized treatment regimes. We first introduce a type of concordance function for prescribing treatment and propose a robust rank regression method for estimating the concordance function. We then find treatment regimes, up to a threshold, to maximize the concordance function, named prescriptive index. Finally, within the class of treatment regimes that maximize the concordance function, we find the optimal threshold to maximize the value function. We establish the convergence rate and asymptotic normality of the proposed estimator for parameters in the prescriptive index. An induced smoothing method is developed to estimate the asymptotic variance of the proposed estimator. We also establish the

Indexed as

ConcordanceOptimal treatment regimePropensity scoreRank estimationValue function

Identifiers

PMID29358898
PMCPMC5774868

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.