Evidence map›Paper›PMID 29358890›Full record

SynthesisWorld journal of gastroenterology2018

Probiotic monotherapy and

Giuseppe Losurdo, Rossella Cubisino, Michele Barone, Mariabeatrice Principi, Gioacchino Leandro, Enzo Ierardi, Alfredo Di Leo

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in World journal of gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 3 pooled it
10.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 3 syntheses or guidelines pooled it, 102 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Efficacy of Pyloshot in combination with standard four-drug antimicrobial treatment forJGH open : an open access journal of gastroenterology and hepatology · 2024
    Article
  14. Review
  15. Review
  16. A review for non-antibiotic treatment ofFrontiers in microbiology · 2024
    Review
  17. Frontiers in immunology · 2024
    Review
  18. Probiotics and autoprobiotics for treatment ofWorld journal of clinical cases · 2023
    Review
  19. Review
  20. Newer, Older, and Alternative Agents for the Eradication ofAntibiotics (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Giuseppe LosurdoSection of Gastroenterology, Department of Emergency and Organ Transplantation, University "Aldo Moro", Piazza Giulio Cesare, Bari 70124, Italy.
Rossella CubisinoSection of Gastroenterology, Department of Emergency and Organ Transplantation, University "Aldo Moro", Piazza Giulio Cesare, Bari 70124, Italy.
Michele BaroneSection of Gastroenterology, Department of Emergency and Organ Transplantation, University "Aldo Moro", Piazza Giulio Cesare, Bari 70124, Italy.
Mariabeatrice PrincipiSection of Gastroenterology, Department of Emergency and Organ Transplantation, University "Aldo Moro", Piazza Giulio Cesare, Bari 70124, Italy.
Gioacchino LeandroNational Institute of Gastroenterology, "S De Bellis" Research Hospital, Via Turi, Castellana Grotte (BA) 70013, Italy.
Enzo IerardiSection of Gastroenterology, Department of Emergency and Organ Transplantation, University "Aldo Moro", Piazza Giulio Cesare, Bari 70124, Italy. e.ierardi@virgilio.it.
Alfredo Di LeoSection of Gastroenterology, Department of Emergency and Organ Transplantation, University "Aldo Moro", Piazza Giulio Cesare, Bari 70124, Italy.
University of Bari Aldo Moro · ITGastroenterology Hospital "Saverio de Bellis" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo define probiotic monotherapy effect on

methodsMethods of analysis and inclusion criteria were based on PRISMA recommendations. Relevant publications were identified by searching PubMed, MEDLINE, Science Direct, and EMBASE. The end-point was to estimate eradication rate and urea breath test delta value before and after probiotic monotherapy across all studies and, overall, with a pooled data analysis. Adverse events of probiotic therapy were evaluated. The data were expressed as proportions/percentages, and 95%CIs were calculated. For continuous variables, we evaluated the weighted mean difference. Odd ratios (ORs) were calculated according to the Peto method for the comparison of eradication rates between probiotics and placebo.

resultsEleven studies were selected. Probiotics eradicated

conclusionProbiotics alone show a minimal effect on

Indexed as

AdolescentAdultAgedBreath TestsChildChi-Square DistributionFemaleHelicobacter InfectionsHelicobacter pyloriHumansMaleMiddle AgedOdds RatioProbioticsRisk FactorsTreatment OutcomeBreath testEradicationHelicobacter pyloriMeta-analysisProbiotics

Identifiers

PMID29358890
PMCPMC5757118
OpenAlexW2781817595

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.