Evidence map›Paper›PMID 29358867›Full record

Observational studyWorld journal of gastroenterology2017

Association between acute pancreatitis and small intestinal bacterial overgrowth assessed by hydrogen breath test.

Mei Zhang, Hong-Ming Zhu, Fang He, Bang-Yi Li, Xiao-Cui Li

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Frequency and predictors of small intestinal bacterial overgrowth in acute pancreatitis.World journal of gastrointestinal pharmacology and therapeutics · 2026
    Article
  4. Review
  5. Article
  6. Epidemiology of small intestinal bacterial overgrowth.World journal of gastroenterology · 2023
    Review
  7. Article
  8. Article
  9. Article
  10. Intensive management of severe acute pancreatitis.Annals of translational medicine · 2019
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Mei ZhangDepartment of Gastroenterology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China zhang2955@sina.com.
Hong-Ming ZhuDepartment of Gastroenterology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
Fang HeDepartment of Gastroenterology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
Bang-Yi LiDepartment of Gastroenterology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
Xiao-Cui LiDepartment of Gastroenterology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
Beijing Xuanwu Traditional Chinese Medicine Hospital · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo elucidate the effects of small intestinal bacterial overgrowth (SIBO) on the severity and complications of acute pancreatitis (AP).

methodsIn total, 208 patients with AP as defined by the revised Atlanta classification were admitted to Xuanwu Hospital of Capital Medical University from 2013 to 2016. All patients were admitted within 72 h of AP onset. The hydrogen breath test was performed 7 d after AP onset to detect hydrogen production and evaluate the development of SIBO. The incidence of SIBO was analyzed in patients with AP of three different severity grades. The association between SIBO and complications of AP was also assessed.

resultsOf the 27 patients with severe AP (SAP), seven (25.92%) developed SIBO. Of the 86 patients with moderately severe AP (MSAP), 22 (25.58%) developed SIBO. Of the 95 patients with mild AP (MAP), eight (8.42%) developed SIBO. There were significant differences in the rates of SIBO among patients with AP of different severities. Additionally, more severe AP was associated with higher rates of SIBO positivity (

conclusionSIBO occurs more frequently in patients with MSAP or SAP than in those with MAP, usually ≤ 72 h after AP onset. Additionally, SIBO is associated with organ failure.

Indexed as

AdultAgedBacteriaBacterial InfectionsBreath TestsFemaleHumansHydrogenIncidenceIntestine, SmallMaleMiddle AgedPancreatitisSeverity of Illness IndexHydrogenComplicationHydrogen breath testSevere acute pancreatitisSmall intestinal bacterial overgrowth

Identifiers

PMID29358867
PMCPMC5752719
OpenAlexW2778562115

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.