ArticleNature communications2018
Fluid network dynamics in the prefrontal cortex during multiple strategy switching.
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Offline generative network reconfiguration guides insight-like accelerated learning by assimilation into schema in rats.Nature communications · 2026Article
- Article
- Prefrontal modulation of striatal engagement: a hierarchical framework for goal-directed behavior.Communications biology · 2026Review
- Hippocampus supports multi-task reinforcement learning under partial observability.Nature communications · 2025Article
- Rhythmic modulation of dorsal hippocampus across distinct behavioral timescales during spatial set-shifting.bioRxiv : the preprint server for biology · 2025Article
- Prefrontal cortex synchronization with the hippocampus and parietal cortex is strategy-dependent during spatial learning.Communications biology · 2025Article
- Population-level coding of avoidance learning in medial prefrontal cortex.Nature neuroscience · 2024Article
- Flexible decision-making is related to strategy learning, vicarious trial and error, and medial prefrontal rhythms during spatial set-shifting.Learning & memory (Cold Spring Harbor, N.Y.) · 2024Article
- A persistent prefrontal reference frame across time and task rules.Nature communications · 2024Article
- Neuronal tuning to threat exposure remains stable in the mouse prefrontal cortex over multiple days.PLoS biology · 2024Article
- Large-scale coupling of prefrontal activity patterns as a mechanism for cognitive control in health and disease: evidence from rodent models.Frontiers in neural circuits · 2024Review
- Article
- Independent response modulation of visual cortical neurons by attentional and behavioral states.Neuron · 2022Article
- Cognition and the single neuron: How cell types construct the dynamic computations of frontal cortex.Current opinion in neurobiology · 2022Review
- Recent Advances at the Interface of Neuroscience and Artificial Neural Networks.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Review
- Understanding ethanol's acute effects on medial prefrontal cortex neural activity using state-space approaches.Neuropharmacology · 2021Review
- The population doctrine in cognitive neuroscience.Neuron · 2021Review
- Coordinated Prefrontal State Transition Leads Extinction of Reward-Seeking Behaviors.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Review
- Dorsomedial prefrontal cortex and hippocampus represent strategic context even while simultaneously changing representation throughout a task session.Neurobiology of learning and memory · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Coordinated shifts of neuronal activity in the prefrontal cortex are associated with strategy adaptations in behavioural tasks, when animals switch from following one rule to another. However, network dynamics related to multiple-rule changes are scarcely known. We show how firing rates of individual neurons in the prelimbic and cingulate cortex correlate with the performance of rats trained to change their navigation multiple times according to allocentric and egocentric strategies. The concerted population activity exhibits a stable firing during the performance of one rule but shifted to another neuronal firing state when a new rule is learnt. Interestingly, when the same rule is presented a second time within the same session, neuronal firing does not revert back to the original neuronal firing state, but a new activity-state is formed. Our data indicate that neuronal firing of prefrontal cortical neurons represents changes in strategy and task-performance rather than specific strategies or rules.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.