Evidence map›Paper›PMID 29358693›Full record

ArticleScientific reports2018

Proteomic evidences for microcystin-RR-induced toxicological alterations in mice liver.

Ashutosh Kumar Rai, Rupesh Chaturvedi, Ashok Kumar

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 14 citations in OpenAlex.

  1. Microcystins can be extracted from Microcystis aeruginosa using amino acid-derived biosurfactants.Environmental science and pollution research international · 2022
    Article
  2. Differences in Abnormal Water Metabolism between SD Rats and KM Mice Intoxicated by Microcystin-RR.International journal of environmental research and public health · 2021
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Ashutosh Kumar RaiSchool of Biotechnology, Institute of Science, Banaras Hindu University, Varanasi, 221005, India. akraibiotech@gmail.com.
Rupesh ChaturvediSchool of Biotechnology, Jawaharlal Nehru University, New Delhi, 110067, India.
Ashok KumarSchool of Biotechnology, Institute of Science, Banaras Hindu University, Varanasi, 221005, India. kasokbt@rediffmail.com.
Jawaharlal Nehru University · INImam Abdulrahman Bin Faisal University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study deals with the isolation and purification of an important variant of microcystins namely microcystin-RR (MCYST-RR) from Microcystis aeruginosa and reports its effects on mice liver protein profile and cellular functions. Protein profiling by 2-dimensional gel electrophoresis revealed changes in the number and accumulation of protein spots in liver of mice treated with different concentrations of MCYST-RR. Untreated (control) mice liver showed 368 protein spots while the number was 355, 348 and 332 in liver of mice treated with 200, 300 and 400 µg kg body wt

Indexed as

AnimalsApoptosisCarcinogensLiverMaleMiceMice, Inbred BALB CMicrocystinsMicrocystisProteomeCarcinogensMicrocystinsProteome

Identifiers

PMID29358693
PMCPMC5778043
OpenAlexW2783432750

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.