ArticleMolecular & cellular proteomics : MCP2018
Simple, scalable, and ultrasensitive tip-based identification of protease substrates.
Article in Molecular & cellular proteomics : MCP, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed.
- Data Processing and Analysis in Positional Proteomics.Proteomics · 2025Review
- Spermidine supplementation and protein restriction protect from organismal and brain aging independently.Aging · 2025Article
- Improved Coverage of the N-Terminome by Combining ChaFRADIC with Alternative Proteases.Methods in molecular biology (Clifton, N.J.) · 2023Article
- A Non-Hazardous Deparaffinization Protocol Enables Quantitative Proteomics of Core Needle Biopsy-Sized Formalin-Fixed and Paraffin-Embedded (FFPE) Tissue Specimens.International journal of molecular sciences · 2022Article
- Protein Processing in Plant Mitochondria Compared to Yeast and Mammals.Frontiers in plant science · 2022Review
- Mapping Cell Surface Proteolysis with Plasma Membrane-Targeted Subtiligase.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Proteomics: A Tool to Study Platelet Function.International journal of molecular sciences · 2021Review
- Spatially Resolved Tagging of Proteolytic Neo-N termini with Subtiligase-TM.The Journal of membrane biology · 2021Article
- Article
- The quest for substrates and binding partners: A critical barrier for understanding the role of ADAMTS proteases in musculoskeletal development and disease.Developmental dynamics : an official publication of the American Association of Anatomists · 2021Review
- Phosphoproteomics of short-term hedgehog signaling in human medulloblastoma cells.Cell communication and signaling : CCS · 2020Article
- Mild proteasomal stress improves photosynthetic performance in Arabidopsis chloroplasts.Nature communications · 2020Article
- Sensitive Determination of Proteolytic Proteoforms in Limited Microscale Proteome Samples.Molecular & cellular proteomics : MCP · 2019Article
- Simple Tip-Based Sample Processing Method for Urinary Proteomic Analysis.Analytical chemistry · 2019Article
- New beginnings and new ends: methods for large-scale characterization of protein termini and their use in plant biology.Journal of experimental botany · 2019Review
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Proteases are in the center of many diseases, and consequently, proteases and their substrates are important drug targets as represented by an estimated 5-10% of all drugs under development. Mass spectrometry has been an indispensable tool for the discovery of novel protease substrates, particularly through the proteome-scale enrichment of so-called N-terminal peptides representing endogenous protein N termini. Methods such as combined fractional diagonal chromatography (COFRADIC)
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Registered trials
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