Evidence map›Paper›PMID 29358328›Full record

ArticleThe Journal of biological chemistry2018

A human xenobiotic nuclear receptor contributes to nonresponsiveness of

Ella Bhagyaraj, Drishti Tiwari, Nancy Ahuja, Ravikanth Nanduri, Ankita Saini, Rashi Kalra, Sumit Kumar, Ashok Kumar Janmeja, Pawan Gupta

Open access · hybridAbstract readComparative Study
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Next-generation rifamycins for the treatment of mycobacterial infections.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Article
  5. High and Low Levels ofInternational journal of molecular sciences · 2023
    Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ella BhagyarajFrom the Department of Molecular Biology, CSIR-Institute of Microbial Technology, Sector 39 A, Chandigarh 160036 and.
Drishti TiwariFrom the Department of Molecular Biology, CSIR-Institute of Microbial Technology, Sector 39 A, Chandigarh 160036 and.
Nancy AhujaFrom the Department of Molecular Biology, CSIR-Institute of Microbial Technology, Sector 39 A, Chandigarh 160036 and.
Ravikanth NanduriFrom the Department of Molecular Biology, CSIR-Institute of Microbial Technology, Sector 39 A, Chandigarh 160036 and.
Ankita SainiFrom the Department of Molecular Biology, CSIR-Institute of Microbial Technology, Sector 39 A, Chandigarh 160036 and.
Rashi KalraFrom the Department of Molecular Biology, CSIR-Institute of Microbial Technology, Sector 39 A, Chandigarh 160036 and.
Sumit KumarFrom the Department of Molecular Biology, CSIR-Institute of Microbial Technology, Sector 39 A, Chandigarh 160036 and.
Ashok Kumar Janmejathe Government Medical College and Hospital, Chandigarh 160030, India.
Pawan GuptaFrom the Department of Molecular Biology, CSIR-Institute of Microbial Technology, Sector 39 A, Chandigarh 160036 and pawan@imtech.res.in.
Institute of Microbial Technology · INGovernment Medical College and Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Drug Resistance, BacterialAnimalsAntibiotics, AntitubercularATP-Binding Cassette TransportersCells, CulturedGene Expression RegulationGenes, ReporterGene Transfer TechniquesHost-Pathogen InteractionsHumansKetoconazoleLungMacrophagesMaleMice, Inbred C57BLMicrobial ViabilityAntibiotics, AntitubercularATP-Binding Cassette TransportersKetoconazoleNR1I2 protein, humanPregnane X ReceptorRecombinant ProteinsRifampinDrug nonresponsivenessdrug resistancedrug transportMycobacterium tuberculosisnuclear receptorPXRtuberculosis

Identifiers

PMID29358328
PMCPMC5846149
OpenAlexW2784870082

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.