Evidence map›Paper›PMID 29357928›Full record

ArticleStem cell research & therapy2018

Evaluation of ex vivo produced endothelial progenitor cells for autologous transplantation in primates.

Meng Qin, Xin Guan, Yu Zhang, Bin Shen, Fang Liu, Qingyu Zhang, Yupo Ma, Yongping Jiang

Open access · goldAbstract read
In one paragraph

Article in Stem cell research & therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Adult Stem Cell Therapy as Regenerative Medicine for End-Stage Liver Disease.Advances in experimental medicine and biology · 2022
    Article
  5. Therapeutic Potential of Endothelial Progenitor Cells in Pulmonary Diseases.American journal of respiratory cell and molecular biology · 2021
    Review
  6. Article
  7. Article
  8. Article
  9. Safety and efficacy of ex vivo expanded CD34Stem cell research & therapy · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Meng QinBiopharmaceutical R&D Center, Chinese Academy of Medical Sciences & Peking Union Medical College, Suzhou, 215126, China.
Xin GuanBiopharmaceutical R&D Center, Chinese Academy of Medical Sciences & Peking Union Medical College, Suzhou, 215126, China.
Yu ZhangBiopharmaceutical R&D Center, Chinese Academy of Medical Sciences & Peking Union Medical College, Suzhou, 215126, China.
Bin ShenBiopharmaceutical R&D Center, Chinese Academy of Medical Sciences & Peking Union Medical College, Suzhou, 215126, China.
Fang LiuWest China Hospital, University of Sichuan, Chengdu, 610041, China.
Qingyu ZhangBiopharmaceutical R&D Center, Chinese Academy of Medical Sciences & Peking Union Medical College, Suzhou, 215126, China.
Yupo MaBiopharmaceutical R&D Center, Chinese Academy of Medical Sciences & Peking Union Medical College, Suzhou, 215126, China.
Yongping JiangBiopharmaceutical R&D Center, Chinese Academy of Medical Sciences & Peking Union Medical College, Suzhou, 215126, China. yjiang@biopharmagen.com.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNStony Brook University Hospital · USWest China Hospital of Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAutologous transplantation of endothelial progenitor cells (EPCs) is a promising therapeutic approach in the treatment of various vascular diseases. We previously reported a two-step culture system for scalable generation of human EPCs derived from cord blood CD34

methodsThe human and nonhuman primate EPCs from mobilized PB CD34

resultsThe mobilized PB CD34

conclusionsWe successfully applied our previous two-step culture system for the generation of primate EPCs from mobilized PB CD34

Indexed as

AdultAnimalsAntigens, CD34Cell- and Tissue-Based TherapyCell Culture TechniquesCell DifferentiationCells, CulturedEndothelial Progenitor CellsFetal BloodHumansLipoproteins, LDLLiverMacaca fascicularisMaleNitric OxideNitric Oxide Synthase Type IIIacetyl-LDLAntigens, CD34Lipoproteins, LDLNitric OxideNitric Oxide Synthase Type IIINOS3 protein, humanEndothelial progenitor cellsHepatic sinusoidal endothelium injuryMobilized peripheral bloodNonhuman primates

Identifiers

PMID29357928
PMCPMC5778763
OpenAlexW2793524926

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.