ArticleBMC musculoskeletal disorders2018
With axial loading during MRI diurnal T2-value changes in lumbar discs are neglectable: a cross sectional study.
Article in BMC musculoskeletal disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Compositional magnetic resonance imaging in the evaluation of the intervertebral disc: Axial vs sagittal TJournal of orthopaedic research : official publication of the Orthopaedic Research Society · 2020Trial
- Load-induced alterations in posterior parts of intervertebral discs in patients with load-induced pain during MRI; a detailed study using T2 maps.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Effects of axial loading and positions on lumbar spinal stenosis: an MRI study using a new axial loading device.Skeletal radiology · 2025Article
- Axial loading lumbar magnetic resonance imaging with a new device in asymptomatic individuals.Quantitative imaging in medicine and surgery · 2023Article
- Lumbar vertebral T2-relaxation time investigated with T2-mapping at multiple time points in a day demonstrate large individual variations.Diagnostic and interventional radiology (Ankara, Turkey) · 2022Article
- Differentiating brucella spondylitis from tuberculous spondylitis by the conventional MRI and MR T2 mapping: a prospective study.European journal of medical research · 2021Article
- Different disc characteristics between young elite skiers with diverse training histories revealed with a novel quantitative magnetic resonance imaging method.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2021Article
- Low back pain patients and controls display functional differences in endplates and vertebrae measured with T2-mapping.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2019Article
- Axial loading during MRI reveals deviant characteristics within posterior IVD regions between low back pain patients and controls.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2018Article
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5 authors.
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Abstract
backgroundAxial loading during MRI (alMRI) combined with T2 mapping recently was shown as a promising method to reveal biomechanical intervertebral disc (IVD) characteristics. This feasibility study aims to investigate whether there is a diurnal variation in the IVD T2-value when using alMRI. This is of importance for the planning of when to perform alMRI investigations and for interpretations of alMRI findings in relation to clinical symptoms.
methodsSix healthy volunteers (30 lumbar discs), were examined with alMRI at three different sessions during 1 day. To be representative for a low back pain cohort in terms of age and IVD degeneration the included participants had a wide age range (27-63y) and all Pfirrmann grades represented. The T2-values were measured in five IVD regions of interest (ROI). The ROIs were equally large in sagittal plane with ROI1 representing anterior parts of the IVD, ROI5 posterior IVD parts and ROI2-4 the parts in between.
resultsT2-values of the entire IVD varied between 38 and 138 ms at 7 am, 33-143 ms at 11.30 am, and 31-147 ms at 4 pm with large regional IVD variations at all time points. No significant alterations of the T2-values over the day were found, neither for the entire IVD (p = 0.4) nor for the various ROIs (p = 0.2-1.0). Neither when correlated to Pfirrmann grade, any significant diurnal T2-value changes were found.
conclusionsWith alMRI, only minor diurnal T2-value changes were found in the lumbar discs. Nonsignificant and neglectable diurnal changes are advantageous both for research purposes, as well as in the clinical setting, giving comparable and robust data regardless of at what time-point the alMRI is performed.
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