Evidence map›Paper›PMID 29357490›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2018

Chronic low-intensity exercise attenuates cardiomyocyte contractile dysfunction and impaired adrenergic responsiveness in aortic-banded mini-swine.

Jessica A Hiemstra, Adam B Veteto, Michelle D Lambert, T Dylan Olver, Brian S Ferguson, Kerry S McDonald, Craig A Emter, Timothy L Domeier

Open access · bronzeAbstract readEvaluation Study
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

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  15. An "Exercise" in Cardiac Metabolism.Frontiers in cardiovascular medicine · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jessica A HiemstraDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Missouri , Columbia, Missouri.
Adam B VetetoDepartment of Medical Pharmacology and Physiology, School of Medicine, University of Missouri , Columbia, Missouri.
Michelle D LambertDepartment of Medical Pharmacology and Physiology, School of Medicine, University of Missouri , Columbia, Missouri.
T Dylan OlverDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Missouri , Columbia, Missouri.
Brian S FergusonDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Missouri , Columbia, Missouri.
Kerry S McDonaldDepartment of Medical Pharmacology and Physiology, School of Medicine, University of Missouri , Columbia, Missouri.
Craig A EmterDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Missouri , Columbia, Missouri.
Timothy L DomeierDepartment of Medical Pharmacology and Physiology, School of Medicine, University of Missouri , Columbia, Missouri.
University of Missouri · US

Funding

Cardiomyocyte TRPV4 and cardiac dysfunction following ischemia-reperfusion in the aged heart.R01HL136292 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI Timothy Lee Domeier · 2017 to 2026
$3.5M
Coronary Dysfunction, BK Channels, & Exercise in Heart FailureR01HL112998 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI EMTER, CRAIG ALLEN · 2014 to 2018
$1.8M
Cardiomyocyte stretch and intracellular calcium release with advancing ageK01AG041208 · NIA · UNIVERSITY OF MISSOURI-COLUMBIA · PI DOMEIER, TIMOTHY LEE · 2012 to 2016
$545k
NHLBI NIH HHS R01 HL112998NHLBI NIH HHS R01 HL136292NIA NIH HHS K01 AG041208
6 · The paper itself

Abstract

Exercise improves clinical outcomes in patients diagnosed with heart failure with reduced ejection fraction (HFrEF), in part via beneficial effects on cardiomyocyte Ca

Indexed as

Excitation Contraction CouplingMyocardial ContractionPhysical Conditioning, AnimalAnimalsCalciumHeart FailureMaleMyocytes, CardiacSwineSwine, MiniatureCalciumcalciumexcitation-contraction couplingheart failure

Identifiers

PMID29357490
PMCPMC5972453
OpenAlexW2781894023

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.