Evidence map›Paper›PMID 29357443›Full record

Observational studyAmerican journal of physiology. Renal physiology2018

Hyperfiltration, urinary albumin excretion, and ambulatory blood pressure in adolescents with Type 1 diabetes mellitus.

Julie A Lovshin, Marko Škrtić, Petter Bjornstad, Rahim Moineddin, Denis Daneman, David Dunger, Heather N Reich, Farid Mahmud, James Scholey, David Z I Cherney and 1 more

Open access · bronzeAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in American journal of physiology. Renal physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 52 citations in OpenAlex.

  1. Trial
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  6. Review
  7. Article
  8. Glomerular hyperfiltration: part 2-clinical significance in children.Pediatric nephrology (Berlin, Germany) · 2023
    Review
  9. Article
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  11. Review
  12. Article
  13. Article
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Julie A LovshinDivision of Endocrinology and Metabolism, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronoto , Toronto, Ontario , Canada.
Marko ŠkrtićDivision of Nephrology, Department of Medicine, University Health Network, University of Toronto , Toronto, Ontario , Canada.
Petter BjornstadDivision of Nephrology, Department of Medicine, University Health Network, University of Toronto , Toronto, Ontario , Canada.
Rahim MoineddinDepartment of Family and Community Medicine, University of Toronto , Toronto, Ontario , Canada.
Denis DanemanDivision of Endocrinology and Metabolism, Department of Pediatrics, Hospital for Sick Children, University of Toronto , Toronto, Ontario , Canada.
David DungerDepartment of Pediatrics, University of Cambridge , Cambridge , United Kingdom.
Heather N ReichDivision of Nephrology, Department of Medicine, University Health Network, University of Toronto , Toronto, Ontario , Canada.
Farid MahmudDivision of Endocrinology and Metabolism, Department of Pediatrics, Hospital for Sick Children, University of Toronto , Toronto, Ontario , Canada.
James ScholeyDivision of Nephrology, Department of Medicine, University Health Network, University of Toronto , Toronto, Ontario , Canada.
David Z I CherneyDivision of Nephrology, Department of Medicine, University Health Network, University of Toronto , Toronto, Ontario , Canada.
Etienne SochettDivision of Endocrinology and Metabolism, Department of Pediatrics, Hospital for Sick Children, University of Toronto , Toronto, Ontario , Canada.
University of Toronto · CAHospital for Sick Children · CAUniversity Health Network · CAHealth Sciences Centre · CAUniversity of Cambridge · GBUniversity of Colorado Denver · US

Funding

Training Program in Diabetes ResearchT32DK063687 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Andrea Steck · 2002 to 2026
$5.2M
Medical Research Council G0600717Medical Research Council MC_UU_12012/5NIDDK NIH HHS T32 DK063687
6 · The paper itself

Abstract

Adolescents with Type 1 diabetes mellitus (T1DM) are at risk for hyperfiltration and elevated urinary albumin-to-creatinine ratio (ACR), which are early indicators of diabetic nephropathy. Adolescents with T1DM also develop early changes in blood pressure, cardiovascular structure, and function. Our aims were to define the relationships between hyperfiltration, ACR, and 24-h ambulatory blood pressure over time in adolescents with T1DM. Normotensive, normoalbuminuric adolescents ( n = 98) with T1DM underwent baseline and 2-yr 24-h ambulatory blood pressure monitoring, glomerular filtration rate (eGFR) estimated by cystatin C (Larsson equation)

Indexed as

Blood PressureGlomerular Filtration RateAdolescentAge FactorsAlbuminuriaBiomarkersBlood Pressure Monitoring, AmbulatoryCardiovascular DiseasesChildCircadian RhythmCreatinineCystatin CDiabetes Mellitus, Type 1Diabetic NephropathiesFemaleFollow-Up StudiesBiomarkersCreatinineCST3 protein, humanCystatin CGlycated Hemoglobinhemoglobin A1c protein, humanLipoproteins, LDL24-h ambulatory blood pressurealbumin-to-creatinine ratioglomerular filtration ratenephropathyType 1 diabetes

Identifiers

PMID29357443
PMCPMC5966760
OpenAlexW2771422178

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.