Evidence map›Paper›PMID 29357200›Full record

ArticleJournal of magnetic resonance imaging : JMRI2018

Improved detection of fMRI activation in the cerebellum at 7T with dielectric pads extending the imaging region of a commercial head coil.

Manushka V Vaidya, Mariana Lazar, Cem M Deniz, Gillian G Haemer, Gang Chen, Mary Bruno, Daniel K Sodickson, Riccardo Lattanzi, Christopher M Collins

Open access · greenAbstract read
In one paragraph

Article in Journal of magnetic resonance imaging : JMRI, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Intraoperative neurophysiology of the cerebellum: a tabula rasa.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020
    Pooled it
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  5. Metamaterial Antennas Enhance MRI of the Eye and Occipital Brain.Advanced materials (Deerfield Beach, Fla.) · 2026
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  6. Easy-to-useMagnetic resonance in medicine · 2025
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  12. Head-and-neck multichannel B1Magnetic resonance in medicine · 2024
    Article
  13. Review
  14. Review
  15. Article
  16. Neuroimaging at 7 Tesla: a pictorial narrative review.Quantitative imaging in medicine and surgery · 2022
    Review
  17. Article
  18. Article
  19. Article
  20. 7T MR Safety.Journal of magnetic resonance imaging : JMRI · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Manushka V VaidyaCenter for Advanced Imaging Innovation and Research (CAI2R) and Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, New York, USA.ORCID http://orcid.org/0000-0002-1473-2590
Mariana LazarCenter for Advanced Imaging Innovation and Research (CAI2R) and Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, New York, USA.
Cem M DenizCenter for Advanced Imaging Innovation and Research (CAI2R) and Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, New York, USA.
Gillian G HaemerCenter for Advanced Imaging Innovation and Research (CAI2R) and Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, New York, USA.
Gang ChenCenter for Advanced Imaging Innovation and Research (CAI2R) and Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, New York, USA.
Mary BrunoCenter for Advanced Imaging Innovation and Research (CAI2R) and Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, New York, USA.
Daniel K SodicksonCenter for Advanced Imaging Innovation and Research (CAI2R) and Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, New York, USA.
Riccardo LattanziCenter for Advanced Imaging Innovation and Research (CAI2R) and Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, New York, USA.
Christopher M CollinsCenter for Advanced Imaging Innovation and Research (CAI2R) and Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, New York, USA.
Advanced Imaging Research (United States) · US

Funding

TR&D 4: Revealing Microstructure: Biophysical modeling and validation for discovery and clinical careP41EB017183 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Hersh Chandarana · 2014 to 2026
$19.3M
Novel Software Tools for Rational Design and Assessment of MR CoilsR01EB024536 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Riccardo Lattanzi · 2017 to 2026
$5.1M
High-Performance High-Field Parallel MRI.R01EB002568 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SODICKSON, DANIEL K · 2003 to 2014
$4.8M
RF Technology Innovation for Advancing High Field MR.R01EB011551 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI COLLINS, CHRISTOPHER M · 2011 to 2014
$2.7M
Next-Generation RF Coils with High-Permittivity Material for Improved Performance in MRIR01EB021277 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI COLLINS, CHRISTOPHER M · 2016 to 2019
$2.1M
NIBIB NIH HHS P41 EB017183NIBIB NIH HHS R01 EB002568NIBIB NIH HHS R01 EB011551NIBIB NIH HHS R01 EB021277NIBIB NIH HHS R01 EB024536
6 · The paper itself

Abstract

backgroundThere is growing interest in detecting cerebro-cerebellar circuits, which requires adequate blood oxygenation level dependent contrast and signal-to-noise ratio (SNR) throughout the brain. Although 7T scanners offer increased SNR, coverage of commercial head coils is currently limited to the cerebrum. PURPOSE: To improve cerebellar functional MRI (fMRI) at 7T with high permittivity material (HPM) pads extending the sensitivity of a commercial coil. STUDY TYPE: Simulations were used to determine HPM pad configuration and assess radiofrequency (RF) safety. In vivo experiments were performed to evaluate RF field distributions and SNR and assess improvements of cerebellar fMRI. SUBJECTS: Eight healthy volunteers enrolled in a prospective motor fMRI study with and without HPM. FIELD STRENGTH/SEQUENCE: Gradient echo (GRE) echo planar imaging for fMRI, turbo FLASH for flip angle mapping, GRE sequence for SNR maps, and T ASSESSMENT: Field maps, SNR maps, and anatomical images were evaluated for coverage. Simulation results were used to assess SAR levels of the experiment. Activation data from fMRI experiments were compared with and without HPM pads. STATISTICAL TESTS: fMRI data were analyzed using FEAT FSL for each subject followed by group level analysis using paired t-test of acquisitions with and without HPM.

resultsSimulations showed 52% improvement in transmit efficiency in cerebellum with HPM and SAR levels well below recommended limits. Experiments showed 27% improvement in SNR in cerebellum and improvement in coverage on T DATA

conclusionHPM pads can improve cerebellar fMRI at 7T with a commonly-used head coil without compromising RF safety. LEVEL OF EVIDENCE: 2 Technical Efficacy: Stage 1 J. MAGN. RESON. IMAGING 2018;48:431-440.

Indexed as

Magnetic Resonance ImagingAdultBrainComputer SimulationContrast MediaEquipment DesignFemaleHumansImage EnhancementImage Processing, Computer-AssistedMalePhantoms, ImagingProspective StudiesRadio WavesReproducibility of ResultsSignal-To-Noise RatioContrast Mediabrain imagingcerebellumfMRIhigh permittivity materialsSARSNR

Identifiers

PMID29357200
PMCPMC6054823
OpenAlexW2790050156

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.