ArticleHistochemistry and cell biology2018
Growth plate-derived hedgehog-signal-responsive cells provide skeletal tissue components in growing bone.
Article in Histochemistry and cell biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 20 citations in OpenAlex.
- Targeting Gli1Stem cell reviews and reports · 2026Review
- Dissecting Hhip1 FunctionActa histochemica et cytochemica · 2025Article
- Identification of distinct subpopulations of Gli1-lineage cells in the mouse mandible.Journal of anatomy · 2023Article
- Identification of Potential Biomarkers and Small Molecule Drugs for Bisphosphonate-Related Osteonecrosis of the Jaw (BRONJ): An Integrated Bioinformatics Study Using Big Data.International journal of molecular sciences · 2023Article
- A Shifting Paradigm: Transformation of Cartilage to Bone during Bone Repair.Journal of dental research · 2023Review
- Suppressor of fused-restrained Hedgehog signaling in chondrocytes is critical for epiphyseal growth plate maintenance and limb elongation in juvenile mice.Frontiers in cell and developmental biology · 2022Article
- New Insights into Development of Female Reproductive Tract-Hedgehog-Signal Response in Wolffian Tissues Directly Contributes to Uterus Development.International journal of molecular sciences · 2021Article
- Fractions of Shen-Sui-Tong-Zhi Formula Enhance OsteogenesisFrontiers in pharmacology · 2021Article
- In focus in HCB.Histochemistry and cell biology · 2020Article
- TGF-β/Smad2 signalling regulates enchondral bone formation of Gli1Cell proliferation · 2020Article
- Review
- Hedgehog Signaling in Skeletal Development: Roles of Indian Hedgehog and the Mode of Its Action.International journal of molecular sciences · 2020Review
- Chondrogenesis Defines Future Skeletal Patterns Via Cell Transdifferentiation from Chondrocytes to Bone Cells.Current osteoporosis reports · 2020Review
- Recent Insights into Long Bone Development: Central Role of Hedgehog Signaling Pathway in Regulating Growth Plate.International journal of molecular sciences · 2019Review
- In focus in HCB: Hard Tissue Biology.Histochemistry and cell biology · 2018Article
- Microenvironmental Regulation of Chondrocyte Plasticity in Endochondral Repair-A New Frontier for Developmental Engineering.Frontiers in bioengineering and biotechnology · 2018Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Longitudinal bone growth progresses by continuous bone replacement of epiphyseal cartilaginous tissue, known as "growth plate", produced by columnar proliferated- and differentiated-epiphyseal chondrocytes. The endochondral ossification process at the growth plate is governed by paracrine signals secreted from terminally differentiated chondrocytes (hypertrophic chondrocytes), and hedgehog signaling is one of the best known regulatory signaling pathways in this process. Here, to investigate the developmental relationship between longitudinal endochondral bone formation and osteogenic progenitors under the influence of hedgehog signaling at the growth plate, genetic lineage tracing was carried out with the use of Gli1
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.