ArticleInternational journal of legal medicine2018
Forensic application of epidermal AQP3 expression to determination of wound vitality in human compressed neck skin.
Article in International journal of legal medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 4 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 4 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Application of Aquaporins as Markers in Forensic Pathology: A Systematic Review of the Literature.International journal of molecular sciences · 2024Pooled it
- State-of-the-Art on Wound Vitality Evaluation: A Systematic Review.International journal of molecular sciences · 2022Pooled it
- A Clue on the Skin: A Systematic Review on Immunohistochemical Analyses of the Ligature Mark.International journal of environmental research and public health · 2022Pooled it
- Forensic Impact of the Omics Science Involved in the Wound: A Systematic Review.Frontiers in medicine · 2021Pooled it
- Forensic application of CAMP expression for the determination of wound vitality in human compressed neck skin.International journal of legal medicine · 2026Article
- Postmortem mutilation in a case of natural death.Forensic science, medicine, and pathology · 2025Article
- Evaluation of Apoptotic Caspase-3 Immunopositivity in Human Model of Asphyxial Death.International journal of molecular sciences · 2025Article
- Post Mortem Molecular Biomarkers of Asphyxia: A Literature Review.International journal of molecular sciences · 2024Review
- Death on New Year's Eve caused by illegal fireworks-a firework shell.Forensic science, medicine, and pathology · 2024Article
- Forensic application of epidermal expression of HSP27 and HSP70 for the determination of wound vitality in human compressed neck skin.Scientific reports · 2023Article
- FOXO3 Depletion as a Marker of Compression-Induced Apoptosis in the Ligature Mark: An Immunohistochemical Study.International journal of molecular sciences · 2023Article
- Histological examination of carotid artery tissue in cases of ligature strangulation and hanging.Forensic sciences research · 2022Article
- Forensic Application of Epidermal Ubiquitin Expression to Determination of Wound Vitality in Human Compressed Neck Skin.Frontiers in medicine · 2022Article
- Editorial: Skin lesion vitality assessment for forensic science: Current research and new perspectives.Frontiers in medicine · 2022Article
- MiRNAs as New Tools in Lesion Vitality Evaluation: A Systematic Review and Their Forensic Applications.Biomedicines · 2021Review
- Aquaporin 1 and 3 as local vitality markers in mechanical and thermal skin injuries.International journal of legal medicine · 2021Article
- Unusual (self-)injuries in a case of hanging.Forensic science, medicine, and pathology · 2021Article
- Death in the sauna-vitality markers for heat exposure.International journal of legal medicine · 2021Article
- Intrathrombotic appearances of AQP-1 and AQP-3 in relation to thrombus age in murine deep vein thrombosis model.International journal of legal medicine · 2021Article
- An Overview on Actual Knowledge About Immunohistochemical and Molecular Features of Vitality, Focusing on the Growing Evidence and Analysis to Distinguish Between Suicidal and Simulated Hanging.Frontiers in medicine · 2021Review
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
In forensic practices, it is often difficult to determine wound vitality in compression marks of the neck with naked eyes. AQP1 and AQP3 are the major water channels associated with skin. Thus, we immunohistochemically examined the expression of AQP1 and AQP3 in neck skin samples to discuss their forensic applicability to determination of the wound vitality. Skin samples were obtained from 56 neck compression cases (hanging, 35 cases; strangulation, 21 cases). The intact skin from the same individual was taken as a control. Although AQP1 was immnunostained in dermal capillaries in both the neck compression marks and intact skin samples, there was no significant difference in the magnitude of AQP1 expression between both groups. On the contrary, AQP3-positive signals could be faintly detected in uninjured skin samples, and the positive signals seemed more intense in the keratinocytes in compression regions. Morphometrical analyses revealed that the ratio of AQP3-expressed keratinocytes was significantly enhanced in neck compression regions, compared with control groups. From the viewpoints of forensic pathology, immunohistochemical detection of AQP3 in the neck skin can be considered a valuable marker to diagnose the trace of antemortem compression.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.