Evidence map›Paper›PMID 29356887›Full record

ReviewJournal of cancer research and clinical oncology2018

Risk for cancer in living kidney donors and recipients.

Min Wang, Huai Zhang, Dan Zhou, Yong-Chao Qiao, Yan-Hong Pan, Yan-Chao Wang, Hai-Lu Zhao

Open access · greenAbstract readReview
In one paragraph

Review in Journal of cancer research and clinical oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Min WangCenter for Diabetic Systems Medicine, Guangxi Key Laboratory of Excellence, Guilin Medical University, Guilin, 541004, Guangxi, China.ORCID http://orcid.org/0000-0002-6996-6159
Huai ZhangCenter for Diabetic Systems Medicine, Guangxi Key Laboratory of Excellence, Guilin Medical University, Guilin, 541004, Guangxi, China.
Dan ZhouCenter for Diabetic Systems Medicine, Guangxi Key Laboratory of Excellence, Guilin Medical University, Guilin, 541004, Guangxi, China.
Yong-Chao QiaoDepartment of Immunology, School of Basic Medicine, Central South University, Changsha, 410078, Hunan, China.
Yan-Hong PanCenter for Diabetic Systems Medicine, Guangxi Key Laboratory of Excellence, Guilin Medical University, Guilin, 541004, Guangxi, China.
Yan-Chao WangCenter for Diabetic Systems Medicine, Guangxi Key Laboratory of Excellence, Guilin Medical University, Guilin, 541004, Guangxi, China.
Hai-Lu ZhaoCenter for Diabetic Systems Medicine, Guangxi Key Laboratory of Excellence, Guilin Medical University, Guilin, 541004, Guangxi, China. zhaohailu9@126.com.
Guilin Medical University · CNCentral South University · CN

Funding

National Natural Science Foundation of China 81270934National Natural Science Foundation of China 81471054Natural Science Foundation of Guangxi 2016GXNSFBA380009
6 · The paper itself

Abstract

objectiveMalignancy following renal transplantation remains inconsistent with the reported safety of kidney donation during the long-term follow-up.

methodsWe conducted searches of the published literature which included healthy participants, recipients, living kidney donors (LKDs), and the availability of outcome data for malignancy. Eight from 938 potentially relevant studies were analyzed by means of fixed-effects model or random-effects model, as appropriately.

resultsIn 48,950 participants, the follow-up range was 18 months to 20 years, and the mean age of the subjects was approximately 41 years. The incidence rate with 95% confidence interval (CI) for malignancy after kidney transplantation was 0.03 (0.01-0.05) in recipients and 0.03 (0.1-0.07) in LKDs, giving a pooled incidence rate of 0.03 (95% CI 0.02-0.04). LKDs contrasted nondonors by the overall odds ratio and 95% CI for total cancer of 2.80 (2.69-2.92).

conclusionsKidney transplantation was associated with an increased risk of cancer during a long-term follow-up. Long-term risk for cancer in LKDs and kidney recipients should be monitored.

Indexed as

Follow-Up StudiesHumansKidneyKidney TransplantationLiving DonorsNeoplasmsRisk FactorsTransplant RecipientsCancerKidney transplantationLiving kidney donorsLong-term outcomesRecipients

Identifiers

PMID29356887
PMCPMC11813368
OpenAlexW2785231532

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.