Are septic children really just "septic little adults"?

Scott L Weiss, Clifford S Deutschman

Abstract readEditorialComment

In one paragraph

Article in Intensive care medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it

0cells of the map it votes in

5citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

Transcriptional markers classifying Escherichia coli and Staphylococcus aureus induced sepsis in adults: A data-driven approach.PloS one · 2024
Article
Fluid Resuscitation and Inotropic Support in Patients With Septic Shock Treated in Pediatric Emergency Department: An Open-Label Trial.Cureus · 2022
Article
Computerized Clinical Decision Support Systems for the Early Detection of Sepsis Among Pediatric, Neonatal, and Maternal Inpatients: Scoping Review.JMIR medical informatics · 2022
Article
Identification of Pediatric Sepsis for Epidemiologic Surveillance Using Electronic Clinical Data.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2020
Observational
A National Approach to Pediatric Sepsis Surveillance.Pediatrics · 2019
Article

4 · The record

Corrections and comments

Comment on
Prognostic accuracy of age-adapted SOFA, SIRS, PELOD-2, and qSOFA for in-hospital mortality among children with suspected infection admitted to the intensive care unit.2018

5 · Who and what money

Authors and funding

2 authors.

Scott L WeissDepartment of Anesthesiology and Critical Care and the Center for Mitochondrial and Epigenomic Medicine, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, 3401 Civic Center Blvd, Wood Building Suite 6026A, Philadelphia, PA, 19104, USA. WeissS@email.chop.edu.

Clifford S DeutschmanDepartments of Pediatrics and Molecular Medicine, Hoftstra-Northwell School of Medicine, Feinstein Institute for Medical Research, Manhasset, NY, USA.

Funding

Orexinergic Modulation of Experimental SepsisR01GM121102 · NIGMS · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI DEUTSCHMAN, CLIFFORD SCOTT, PAVLOV, VALENTIN ATANASSOV · 2017 to 2020

$1.6M

Mitochondrial Dysfunction in Pediatric SepsisK23GM110496 · NIGMS · CHILDREN'S HOSP OF PHILADELPHIA · PI WEISS, SCOTT L · 2015 to 2018

$723k

NIGMS NIH HHS K23 GM110496NIGMS NIH HHS R01 GM121102

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Shock, SepticAdultChildHumansInfant

Identifiers

PMID29356850

DOI10.1007/s00134-017-5041-4

PMCPMC7269052

What OpenQuestion holds

Textmetadata

LicenceTDM

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.