ArticleAnnals of surgery2018
Functional Trajectories Before and After Major Surgery in Older Adults.
Article in Annals of surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 49 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
49 citing papers in PubMed, 94 citations in OpenAlex.
- Preoperative knee joint hypothermia reduces inflammation and recovery time and increases range of motion after total knee arthroplasty: A randomized controlled trial.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025Trial
- Recovery of physical and mental health within 4 weeks after colorectal surgery: a prospective cohort study.Surgical endoscopy · 2026Article
- Association of pre- and postoperative delirium with functional status at discharge after hip fracture: findings from the Gruppo Italiano di Ortogeriatria (GIOG 2.0) study.European geriatric medicine · 2026Article
- Days at Home After Serious Health Events Among Community-Living Older Persons.Journal of the American Geriatrics Society · 2026Article
- Article
- Recovery Experiences of Older Adults and Their Caregivers After Major Elective Noncardiac Surgery.JAMA network open · 2026Article
- Effect of Branched-Chain Amino Acid-enriched nutritional supplement after exercise on skeletal muscle mass in patients undergoing surgery for gastrointestinal cancer.Progress in rehabilitation medicine · 2026Article
- General Principles of Risk Mitigation before Colorectal Surgery.Clinics in colon and rectal surgery · 2026Review
- The trajectory of patient-reported outcomes after hip preservation surgery: A National Registry Study.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025Article
- End-of-life issues in older adults: Emotional and social factors that shape end-of-life experiences.Advances in psychiatry and behavioral health · 2025Article
- Immediate Mobilisation After Elective Colorectal Surgery-Patients' and Healthcare Professionals' Experiences: A Qualitative Study.Scandinavian journal of caring sciences · 2025Article
- Preliminary Outcomes of a Digital Remote Care Solution for Colorectal Cancer Patients.Cancers · 2025Article
- Effects of Prehabilitation Concurrent Exercise on Functional Capacity in Colorectal Cancer Patients: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2025Review
- Critical Illness, Major Surgery, and Other Hospitalizations and Active and Disabled Life Expectancy.JAMA network open · 2025Article
- Mortality and Function After Hip Fracture or Pneumonia in People With and Without Dementia.Journal of the American Geriatrics Society · 2025Article
- Caregiving Trajectories and Unmet Care Needs in Later Life.The Gerontologist · 2025Article
- Synergistic power of functional foods and exercise in colorectal cancer control: targeting metabolism, mitochondrial function, redox homeostasis, exercise performance, neuroimmune signaling, and brain-gut axis crosstalk.Frontiers in nutrition · 2025Review
- Palliative care in acute care surgery: research challenges and opportunities.Trauma surgery & acute care open · 2025Review
- A single-center prospective cohort study assessing preoperative gait speed assessment as a prognostic tool for morbidity and mortality in frail elderly patients undergoing abdominal surgery.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2025Article
- Co-Developed Logic Model for Surgical Prehabilitation in an Acute Care Setting: A Qualitative Study of Stakeholders' Perspectives.Annals of nutrition & metabolism · 2025Article
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
objectivesWe hypothesized that distinct sets of functional trajectories can be identified in the year before and after major surgery, with unique transition probabilities from pre to postsurgical functional trajectories, and that outcomes would be better among participants undergoing elective versus nonelective surgery.
backgroundMajor surgery is common and can be highly morbid in older persons. The relationship between the course of disability (ie, functional trajectory) before and after surgery in older adults has not been well-studied for most operations.
methodsProspective cohort study of 754 community-living persons 70 years or older. The analytic sample included 250 participants who underwent their first major surgery during the study period.
resultsBefore surgery, 4 functional trajectories were identified: no disability (n = 60, 24.0%), and mild (n = 84, 33.6%), moderate (n = 73, 29.2%), and severe (n = 33, 13.2%) disability. After surgery, 4 functional trajectories were identified: rapid (n = 39, 15.6%), gradual (n = 76, 30.4%), partial (n = 70, 28.0%), and little (n = 57, 22.8%) improvement. Rapid improvement was seen for n = 31 (51.7%) participants with no disability before surgery, but was uncommon among those with mild disability (n = 8, 9.5%) and was not observed in the moderate and severe trajectory groups. For participants with mild to moderate disability before surgery, gradual improvement (n = 46, 54.8%) and partial improvement (n = 36, 49.3%) were most common. Most participants with severe disability (n = 27, 81.8%) before surgery exhibited little improvement. Outcomes were better for participants undergoing elective versus nonelective surgery.
conclusionsFunctional prognosis in the year after major surgery is highly dependent on premorbid function.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.