Evidence map›Paper›PMID 29356245›Full record

ArticleGeriatrics & gerontology international2018

Predicting survival of older community-dwelling individuals according to five estimated glomerular filtration rate equations: The InChianti study.

Andrea Corsonello, Claudio Pedone, Stefania Bandinelli, Luigi Ferrucci, Raffaele Antonelli Incalzi

Abstract read
In one paragraph

Article in Geriatrics & gerontology international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Article
  10. CKD: A Call for an Age-Adapted Definition.Journal of the American Society of Nephrology : JASN · 2019
    Review
  11. Article
  12. Observational
  13. Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Andrea CorsonelloUnit of Geriatric Pharmacoepidemiology, Italian National Research Center on Aging, Cosenza, Italy.ORCID http://orcid.org/0000-0002-7276-3256
Claudio PedoneUnit of Geriatric Medicine, University Campus Biomedico, Rome, Italy.
Stefania BandinelliHealth Agency, Florence, Italy.
Luigi FerrucciNational Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA.
Raffaele Antonelli IncalziUnit of Geriatric Medicine, University Campus Biomedico, Rome, Italy.

Funding

The InChianti StudyZIAAG001050 · NIA · NATIONAL INSTITUTE ON AGING · PI FERRUCCI, LUIGI · 2009 to 2025
$2.1M
Biomarkers of Homestatic Dysregulation in Aging and Chronic DiseaseZIAAG000971 · NIA · NATIONAL INSTITUTE ON AGING · PI FERRUCCI, LUIGI · 2009 to 2025
$1.9M
Intramural NIH HHS Z99 AG999999Intramural NIH HHS ZIA AG001050
6 · The paper itself

Abstract

aimsThere is uncertainty about which estimated glomerular filtration rate eGFR equation to use in older people with respect to the prediction of prognosis. Our aim was: (i) to compare the discriminative capacity of eGFR estimated by different equations with respect to all-cause mortality; and (ii) to identify the eGFR threshold at which the risk of mortality starts to increase for each equation.

methodsWe used data from 828 community-dwelling older adults aged >65 years enrolled in the InCHIANTI study. The outcome measure was all-cause mortality at 9 years. GFR was estimated by five different equations: Chronic Kidney Disease Epidemiological Collaboration (creatinine equation [CKD-EPI

resultsThe best mix of sensitivity, specificity, AUC and C-statistic value in predicting mortality was observed with BIS equations. BIS

conclusionsThe BIS equation discriminates the risk of all-cause mortality better than other equations in older community-dwelling individuals. The eGFR threshold under which mortality starts to increase could change as a function of the equation used. Geriatr Gerontol Int 2018; 18: 607-614.

Indexed as

Glomerular Filtration RateAgedHumansIndependent LivingPredictive Value of TestsRenal Insufficiency, ChronicSurvival AnalysisBerlin Initiative StudyChronic Kidney Disease Epidemiological Collaborationestimated glomerular filtration ratefull age spectrummortality

Identifiers

PMID29356245
PMCPMC5891358

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.