Evidence map›Paper›PMID 29356173›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2018

9-Membered Carbocycles: Strategies and Tactics for their Synthesis.

Tatjana Huber, Raphael E Wildermuth, Thomas Magauer

Abstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Cyclization by Intramolecular Suzuki-Miyaura Cross-Coupling-A Review.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Review
  2. Article
  3. Total Synthesis of Dragocins A-C through Electrochemical Cyclization.Angewandte Chemie (International ed. in English) · 2024
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Evolution of a Strategy for the Total Synthesis of (+)-Cornexistin.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021
    Article
  10. Article
  11. Total Synthesis of (+)-Cornexistin.Angewandte Chemie (International ed. in English) · 2020
    Article
  12. 9-Membered Carbocycles: Strategies and Tactics for their Synthesis.Chemistry (Weinheim an der Bergstrasse, Germany) · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tatjana HuberDepartment of Chemistry and Pharmacy, Ludwig-Maximillians University Munich, Butenandtstrasse 5-13, 81377, Munich, Germany.
Raphael E WildermuthInstitute of Organic Chemistry and Center for Molecular Biosciences, University of Innsbruck, Innrain 80-82, 6020, Innsbruck, Austria.
Thomas MagauerInstitute of Organic Chemistry and Center for Molecular Biosciences, University of Innsbruck, Innrain 80-82, 6020, Innsbruck, Austria.ORCID http://orcid.org/0000-0003-1290-9556

Funding

European Research Council 714049
6 · The paper itself

Abstract

Many natural products comprising a nine-membered carbocyclic core structure exhibit interesting biological effects. However, only a minority have succumbed to their synthesis in the past. The synthesis of functionalized nine-membered carbocycles still remains a challenging goal for synthetic chemists, mainly due to their high ring strain. Different strategies to overcome the unfavorable enthalpic and entropic factors associated with their formation are highlighted in this Concept article. The presented methods are classified into two different categories: (1) the ring-expansion of smaller rings or the ring-contraction of larger rings and (2) the direct cyclization of acyclic precursors.

Indexed as

carbocyclescyclizationfragmentationnine-membered ringring-expansion

Identifiers

PMID29356173
PMCPMC6420057

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.