ArticleGates open research2017
Pre-exposure prophylaxis for HIV-negative persons with partners living with HIV: uptake, use, and effectiveness in an open-label demonstration project in East Africa.
Open access · goldAbstract read
In one paragraph
Article in Gates open research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 3 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed, 3 pooled it
7.1field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
80 citing papers in PubMed, 3 syntheses or guidelines pooled it, 91 citations in OpenAlex.
- Low clinical impact of HIV drug resistance mutations in oral pre-exposure prophylaxis: a systematic review and meta-analysis.AIDS research and therapy · 2024Pooled it
- Discontinuation, suboptimal adherence, and reinitiation of oral HIV pre-exposure prophylaxis: a global systematic review and meta-analysis.The lancet. HIV · 2022Pooled it
- Risk scores for predicting HIV incidence among adult heterosexual populations in sub-Saharan Africa: a systematic review and meta-analysis.Journal of the International AIDS Society · 2022Pooled it
- Behavioral and Structural Interventions for PrEP Adherence Among Young Female Sex Workers from Western Kenya.AIDS and behavior · 2026Trial
- Vaginal Microbiota and Cytokines Among Pregnant and Breastfeeding Women in Clinical Trials of the Dapivirine Vaginal Ring and Oral Tenofovir Disoproxil Fumarate/Emtricitabine.Open forum infectious diseases · 2026Trial
- Correlates of Adherence to Oral and Vaginal Pre-exposure Prophylaxis (PrEP) Among Adolescent Girls and Young Women (AGYW) Participating in the MTN-034/REACH Trial.AIDS and behavior · 2024Trial
- Low selection of HIV PrEP refills at private pharmacies among clients who initiated PrEP at public clinics: findings from a mixed-methods study in Kenya.BMC health services research · 2024Trial
- Behavioral Modeling and its Association with PrEP and ART Use in Ugandan HIV-Serodifferent Couples.AIDS and behavior · 2024Trial
- DELIVER: A Safety Study of a Dapivirine Vaginal Ring and Oral PrEP for the Prevention of HIV During Pregnancy.Journal of acquired immune deficiency syndromes (1999) · 2024Trial
- Efficiency of 6-month PrEP dispensing with HIV self-testing in Kenya: an open-label, randomised, non-inferiority, implementation trial.The lancet. HIV · 2022Trial
- Short- and Long-Term Pharmacologic Measures of HIV Pre-exposure Prophylaxis Use Among High-Risk Men Who Have Sex With Men in HPTN 067/ADAPT.Journal of acquired immune deficiency syndromes (1999) · 2019Trial
- Real-time electronic drug monitoring: experiences from a multinational phase 3 clinical trial to prevent multidrug-resistant TB.IJTLD open · 2026Article
- Dynamic choice HIV prevention with long-acting injectable cabotegravir pre-exposure prophylaxis in east, central, southern, and west Africa: a cost-effectiveness modelling analysis.The lancet. HIV · 2025Article
- Opportunity for cost savings with a novel differentiated model of PrEP delivery: a comparative costing analysis of six-month PrEP supported by interim HIV self-testing and standard of care PrEP dispensing in Kenya.BMC health services research · 2025Article
- Factors associated with awareness of and willingness to use PrEP among stable, heterosexual HIV-serodifferent couples in seven African countries, 2019-2022.Journal of the International AIDS Society · 2025Article
- Getting HIV Pre-exposure Prophylaxis (PrEP) into Private Pharmacies: Global Delivery Models and Research Directions.Current HIV/AIDS reports · 2024Review
- Restarting pre-exposure prophylaxis (PrEP) for HIV: a systematic review and meta-analysis.EClinicalMedicine · 2024Article
- How PrEP delivery was integrated into public ART clinics in central Uganda: A qualitative analysis of implementation processes.PLOS global public health · 2024Article
- Modeled estimates of HIV-serodifferent couples in tuberculosis-affected households in four sub-Saharan African countries.PLOS global public health · 2024Article
- Study design approaches for future active-controlled HIV prevention trials.Statistical communications in infectious diseases · 2024Article
20 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors at 8 institutions in 4 countries.
Renee HeffronDepartment of Epidemiology, University of Washington, Seattle, USA.ORCID https://orcid.org/0000-0001-6039-0352
Kenneth NgureCollege of Health Sciences, Jomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya.
Josephine OdoyoCentres for Microbiology Research , Kenya Medical Research Institute, Nairobi, Kenya.
Nulu BulyaInfectious Diseases Institute, Makerere University, Kampala, Uganda.
Edna TindimwebwaKabwohe Clinical Research Center, Kabwohe, Uganda.ORCID https://orcid.org/0000-0003-4255-2818
Ting HongDepartment of Global Health, University of Washington, Seattle, USA.
Lara KidoguchiDepartment of Global Health, University of Washington, Seattle, USA.
Deborah DonnellDepartment of Global Health, University of Washington, Seattle, USA.ORCID https://orcid.org/0000-0002-0587-7480
Nelly R MugoDepartment of Global Health, University of Washington, Seattle, USA.
Elizabeth A BukusiDepartment of Global Health, University of Washington, Seattle, USA.
Elly KatabiraInfectious Diseases Institute, Makerere University, Kampala, Uganda.
Stephen AsiimweKabwohe Clinical Research Center, Kabwohe, Uganda.
Jennifer MortonDepartment of Global Health, University of Washington, Seattle, USA.
Susan MorrisonDepartment of Global Health, University of Washington, Seattle, USA.
Harald HaugenDepartment of Global Health, University of Washington, Seattle, USA.
Andrew MujugiraInfectious Diseases Institute, Makerere University, Kampala, Uganda.
Jessica E HabererHarvard Medical School - Massachusetts General Hospital, Boston, USA.
Norma C WareDepartment of Global Health and Social Medicine, Harvard Medical School, Boston, USA.ORCID https://orcid.org/0000-0002-5039-9991
Monique A WyattDepartment of Global Health and Social Medicine, Harvard Medical School, Boston, USA.
Mark A MarzinkeDepartment of Medicine, Johns Hopkins University, Baltimore, USA.
Lisa M FrenkelSeattle Children's Research Center, Seattle, USA.
Connie CelumDepartment of Epidemiology, University of Washington, Seattle, USA.ORCID https://orcid.org/0000-0002-8813-3419
Jared M BaetenDepartment of Epidemiology, University of Washington, Seattle, USA.
Partners Demonstration Project Team
University of Washington · USHarvard University · USInfectious Diseases Institute · UGJoint Clinical Research Centre · UGCape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa · ZAJohns Hopkins University · USJomo Kenyatta University of Agriculture and Technology · KEKenya Medical Research Institute · KE
Funding
University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI EDWIN ROBERTO ORELLANA · 1988 to 2026
$104.9MOptimizing Antiretroviral-Based HIV Prevention for HIV Serodiscordant CouplesR01MH095507 · NIMH · UNIVERSITY OF WASHINGTON · PI BAETEN, JARED · 2011 to 2020
$6.1MNIAID NIH HHS P30 AI027757NIMH NIH HHS R01 MH095507
Abstract
PubMed holds no abstract for this paper.
Indexed as
ARTHIV preventionHIV serodiscordant couplesPrEP
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.