Evidence map›Paper›PMID 29355224›Full record

ArticleGates open research2017

Rationale and design of a multi-center, open-label, randomised clinical trial comparing HIV incidence and contraceptive benefits in women using three commonly-used contraceptive methods (the ECHO study).

G Justus Hofmeyr, Charles S Morrison, Jared M Baeten, Tsungai Chipato, Deborah Donnell, Peter Gichangi, Nelly Mugo, Kavita Nanda, Helen Rees, Petrus Steyn and 2 more

Open access · goldAbstract read
In one paragraph

Article in Gates open research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 6 countries.

G Justus Hofmeyr *Effective Care Research Unit, Universities of Witwatersrand and Fort Hare, Eastern Cape Department of Health, East London, South Africa.
Charles S Morrison *Global Health, Population and Nutrition, FHI 360, Durham, NC, USA.ORCID https://orcid.org/0000-0002-9873-3194
Jared M BaetenDepartments of Global Health, Medicine, and Epidemiology, University of Washington, Seattle, WA, USA.
Tsungai ChipatoDepartment of Obstetrics and Gynaecology, University of Zimbabwe, Harare, Zimbabwe.
Deborah DonnellVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.ORCID https://orcid.org/0000-0002-0587-7480
Peter GichangiUniversity of Nairobi, Nairobi, Kenya.
Nelly MugoKenya Medical Research Institute, Nairobi, Kenya.
Kavita NandaGlobal Health, Population and Nutrition, FHI 360, Durham, NC, USA.
Helen ReesWits RHI, University of the Witwatersrand, Johannesburg, South Africa.
Petrus SteynWorld Health Organization, Geneva, Switzerland.
Douglas TaylorGlobal Health, Population and Nutrition, FHI 360, Durham, NC, USA.
ECHO Trial Team
Family Health International 360 · USUniversity of Washington · USInfectious Disease Research Institute · USUniversity of Nairobi · KEUniversity of the Witwatersrand · ZAUniversity of Zimbabwe · ZWWestern Cape Department of Health · ZAWorld Health Organization · CH

Funding

World Health Organization 001
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

contraceptionDMPAeffectivenessHIV acquisitionimplantsIUDrandomized trial

Identifiers

PMID29355224
PMCPMC5771152
OpenAlexW2781219017

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.