Evidence map›Paper›PMID 29354681›Full record

ArticleeNeuro

Lingual Gyrus Surface Area Is Associated with Anxiety-Depression Severity in Young Adults: A Genetic Clustering Approach.

Baptiste Couvy-Duchesne, Lachlan T Strike, Greig I de Zubicaray, Katie L McMahon, Paul M Thompson, Ian B Hickie, Nicholas G Martin, Margaret J Wright

Open access · goldAbstract readTwin Study
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 68 citations in OpenAlex.

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  7. Multi-modal cross-domain self-supervised pre-training for fMRI and EEG fusion.Neural networks : the official journal of the International Neural Network Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Baptiste Couvy-DuchesneQueensland Brain Institute, University of Queensland, Brisbane 4072, Australia.ORCID 0000-0002-0719-9302
Lachlan T StrikeQueensland Brain Institute, University of Queensland, Brisbane 4072, Australia.ORCID 0000-0003-2885-5898
Greig I de ZubicarayInstitute of Health Biomedical Innovations, Queensland Institute of Technology, Brisbane 4006, Australia.ORCID 0000-0003-4506-0579
Katie L McMahonCentre for Advanced Imaging, University of Queensland, Brisbane 4072, Australia.ORCID 0000-0002-6357-615X
Paul M ThompsonImaging Genetics Center, Keck School of Medicine, University of Southern California, Marina del Rey, CA 90292.
Ian B HickieBrain and Mind Research Institute, University of Sydney, Sydney 2050, Australia.
Nicholas G MartinQIMR Berghofer Medical Research Institute, Brisbane 4006, Australia.ORCID 0000-0003-4069-8020
Margaret J WrightQueensland Brain Institute, University of Queensland, Brisbane 4072, Australia.
The University of Queensland · AUQIMR Berghofer Medical Research Institute · AUQueensland University of Technology · AUThe University of Sydney · AUUniversity of Southern California · US

Funding

Mapping the Human Connectome: Structure, Function, and HeritabilityU54MH091657 · NIMH · WASHINGTON UNIVERSITY · PI UGURBIL, KAMIL, VAN ESSEN, DAVID C · 2010 to 2014
$34.7M
TR&D3: Intrinsic Surface MappingP41EB015922 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI VAN HORN, JOHN DARRELL · 2012 to 2022
$14.1M
Training U54EB020403 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI THOMPSON, PAUL M · 2014 to 2018
$10.1M
Genetic influences on the brain: A twin imaging studyR01HD050735 · NICHD · QUEENSLAND INSTITUTE OF MEDICAL RESEARCH · PI WRIGHT, MARGARET JANE · 2007 to 2011
$2.6M
NIBIB NIH HHS P41 EB015922NIBIB NIH HHS U54 EB020403NICHD NIH HHS R01 HD050735NIMH NIH HHS U54 MH091657
6 · The paper itself

Abstract

Here we aimed to identify cortical endophenotypes for anxiety-depression. Our data-driven approach used vertex-wise genetic correlations (estimated from a twin sample: 157 monozygotic and 194 dizygotic twin pairs) to parcellate cortical thickness (CT) and surface area (SA) into genetically homogeneous regions (Chen et al., 2013). In an overlapping twin and sibling sample (

Indexed as

AdultAnxietyCluster AnalysisDepressionEndophenotypesFemaleGenetic Predisposition to DiseaseHumansMagnetic Resonance ImagingMaleOccipital LobeSiblingsYoung Adultcortical surface areadepression anxietyendophenotypegenetic clusteringlingual gyrusnonlinear effect

Identifiers

PMID29354681
PMCPMC5773884
OpenAlexW2783409364

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.