Evidence map›Paper›PMID 29354648›Full record

ArticleMicrobial cell (Graz, Austria)2017

The cytosolic glyoxalases of

Cletus A Wezena, Romy Alisch, Alexandra Golzmann, Linda Liedgens, Verena Staudacher, Gabriele Pradel, Marcel Deponte

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbial cell (Graz, Austria), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Plasmodium falciparum In Vitro Drug Resistance Selections and Gene Editing.Methods in molecular biology (Clifton, N.J.) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Cletus A WezenaDepartment of Parasitology, Ruprecht-Karls University, D-69120 Heidelberg, Germany.
Romy AlischDepartment of Parasitology, Ruprecht-Karls University, D-69120 Heidelberg, Germany.
Alexandra GolzmannDivision of Cellular and Applied Infection Biology, Institute of Zoology, RWTH Aachen University, D-52074 Aachen, Germany.
Linda LiedgensDepartment of Parasitology, Ruprecht-Karls University, D-69120 Heidelberg, Germany.
Verena StaudacherDepartment of Parasitology, Ruprecht-Karls University, D-69120 Heidelberg, Germany.
Gabriele PradelDivision of Cellular and Applied Infection Biology, Institute of Zoology, RWTH Aachen University, D-52074 Aachen, Germany.
Marcel DeponteDepartment of Parasitology, Ruprecht-Karls University, D-69120 Heidelberg, Germany.
Heidelberg University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The enzymes glyoxalase 1 and 2 (Glo1 and Glo2) are found in most eukaryotes and catalyze the glutathione-dependent conversion of 2-oxoaldehydes to 2-hydroxycarboxylic acids. Four glyoxalases are encoded in the genome of the malaria parasite

Indexed as

CRISPR/Cas9drug targetglyoxalasemalariaPlasmodium falciparum

Identifiers

PMID29354648
PMCPMC5772037
OpenAlexW2768265789

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.