Evidence map›Paper›PMID 29354583›Full record

ArticleAnnals of rehabilitation medicine2017

Long-Term Outcome of Amyotrophic Lateral Sclerosis in Korean Subjects.

Mi Ri Suh, Won Ah Choi, Young-Chul Choi, Jang Woo Lee, Jung Hwa Hong, Jihyun Park, Seong-Woong Kang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of rehabilitation medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Mi Ri SuhDepartment of Medicine, The Graduate School, Yonsei University, Seoul, Korea.ORCID https://orcid.org/0000-0003-1759-9198
Won Ah ChoiDepartment of Rehabilitation Medicine and Rehabilitation Institute of Neuromuscular Disease, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-0403-8869
Young-Chul ChoiDepartment of Neurology, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-5525-6861
Jang Woo LeeDepartment of Physical Medicine and Rehabilitation, National Health Insurance Service Ilsan Hospital, Goyang, Korea.ORCID https://orcid.org/0000-0002-2634-0375
Jung Hwa HongResearch Institute, National Health Insurance Service Ilsan Hospital, Goyang, Korea.ORCID https://orcid.org/0000-0003-0321-0751
Jihyun ParkDepartment of Rehabilitation Medicine and Rehabilitation Institute of Neuromuscular Disease, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-2172-1072
Seong-Woong KangDepartment of Rehabilitation Medicine and Rehabilitation Institute of Neuromuscular Disease, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-7279-3893
Yonsei University · KRNational Health Insurance Service Ilsan Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo report the latest long-term outcome of amyotrophic lateral sclerosis (ALS) and to analyze the predictors of prognosis.

methodsSubjects who were diagnosed with ALS between January 2005 and December 2009 at a single institute were followed up until death or up to December 2014. Data regarding age, sex, date of onset, date of diagnosis, presence of bulbar symptoms on onset, date of initiation of non-invasive ventilation (NIV), and the date of tracheostomy were collected. Survival was assessed using Kaplan-Meier curves and multivariate analyses of the risk of death were performed using the Cox proportional hazards model.

resultsAmong 212 suspicious subjects, definite ALS was diagnosed in 182 subjects. The survival rate at 3 and 5 years from onset was 61.5% and 40.1%, respectively, and the survival rate at 3 and 5 years post-diagnosis was 49.5% and 24.2%, respectively. Further, 134 patients (134/182, 73.6%) were initiated on NIV, and among them, 90 patients (90/182, 49.5%) underwent tracheostomy. Male gender and onset age of ≥65 years were independent predictors of adverse survival.

conclusionThe analysis of long term survival in ALS showed excellent outcomes considering the overall poor prognosis of this disease.

Indexed as

Amyotrophic lateral sclerosisPrognosisSurvival

Identifiers

PMID29354583
PMCPMC5773426
OpenAlexW2793217723

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.