ArticleIntegrated pharmacy research & practice2017
Antihypertensive drug prescription patterns and their impact on outcome of blood pressure in Ethiopia: a hospital-based cross-sectional study.
Article in Integrated pharmacy research & practice, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Uncontrolled hypertension among hypertensive patients in Sub-Saharan Africa: A systematic review and meta-analysis.PloS one · 2024Pooled it
- Prevalence of uncontrolled hypertension and contributing factors in Ethiopia: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2024Pooled it
- Uncontrolled hypertension in Ethiopia: a systematic review and meta-analysis of institution-based observational studies.BMC cardiovascular disorders · 2020Pooled it
- Incidence and risk factors of calcium channel blocker-related edema in hypertensive patients: A Multicenter retrospective cohort study.PloS one · 2026Article
- Integrated multi-month dispensing of antihypertensive and antiretroviral therapy to sustain hypertension and HIV control.Journal of human hypertension · 2023Article
- Prescribing pattern of anti-hypertensive medications among hypertensive outpatients at selected hospitals of South Gondar Zone, Amhara, Ethiopia: a hospital based cross sectional study.BMC pharmacology & toxicology · 2022Article
- Non-persistence to antihypertensive drug therapy in Lithuania.European journal of clinical pharmacology · 2022Article
- Article
- Rate of blood pressure control and its determinants among adult hypertensive patients at Jimma University Medical Center, Ethiopia: Prospective cohort study.SAGE open medicine · 2021Article
- Cost of Hypertension Illness and Associated Factors Among Patients Attending Hospitals in Southwest Shewa Zone, Oromia Regional State, Ethiopia.ClinicoEconomics and outcomes research : CEOR · 2020Article
- Treating patients with hypertension in Indonesia's primary health care centre: A challenging condition.Global cardiology science & practice · 2019Article
- Prescribing trend in cardiovascular patients at Ethiopian university hospital: The number of medications and implication on the clinical improvement.Pharmacology research & perspectives · 2019Article
- Antihypertensive Prescription Pattern and Compliance to JNC 7 and JNC 8 at Tertiary Care Government Hospital, Hyderabad, India: A Cross-sectional Retrospective Study.Hospital pharmacy · 2018Article
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3 authors.
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Abstract
backgroundIrrational prescription is strongly associated with poor control of hypertension. The present study aimed to evaluate antihypertensive drug prescription trends and to measure their impact on the level of blood pressure (BP) control in Gondar University Hospital, Gondar, Ethiopia.
methodsA hospital-based retrospective cross-sectional study was conducted from May 30 to June 30, 2016. All hypertensive patients on medication were included. A structured data abstraction form was prepared to gather the necessary information. The prescription patterns and BP level were measured retrospectively. A binary logistic regression was computed to determine the effect of different prescription patterns on BP control.
resultsA total of 596 hypertension patients were recruited for the study; of them, 561(94%) met the study criteria. The mean age of the respondents was 55.96±14.6 years. Females constituted 58.2% of the study population. Approximately fifty percent of the prescriptions were monotherapies. Twice-daily dosing was associated with lower risk of uncontrolled hypertension (crude odds ratio [COR] =0.51[0.15-0.73], adjusted odds ratio [AOR] =0.69[0.163-0.91]). Monthly appointment was linked with a nearly 90% reduced incidence of uncontrolled BP (COR =0.15[0.04-0.73], AOR =0.093[0.024-0.359]).
conclusionMonotherapies were the most frequently prescribed regimens. Twice-daily dosing and monthly appointments were associated with low incidence of uncontrolled BP. Clinicians should be vigilant in adjusting the frequency of dosing and should fix appointment date in consultation with their patients.
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