Evidence map›Paper›PMID 29354282›Full record

ArticleNPJ systems biology and applications2018

Regulatory feedback response mechanisms to phosphate starvation in rice.

Ishan Ajmera, Jing Shi, Jitender Giri, Ping Wu, Dov J Stekel, Chungui Lu, T Charlie Hodgman

Abstract read
In one paragraph

Article in NPJ systems biology and applications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Biogenesis, Mode of Action and the Interactions of Plant Non-Coding RNAs.International journal of molecular sciences · 2023
    Review
  4. Article
  5. Frontiers in plant science · 2020
    Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ishan AjmeraSchool of Biosciences, The University of Nottingham, Sutton Bonington Campus, Sutton Bonington, Loughborough, LE12 5RD UK.ORCID 0000-0002-8770-5235
Jing Shi3State Key Laboratory of Plant Physiology and Biochemistry, College of Life Science, Zhejiang University, Hangzhou, China.
Jitender GiriNational Institute of Plant Genome Research, Aruna Asaf Ali Marg, New Delhi, India.
Ping Wu3State Key Laboratory of Plant Physiology and Biochemistry, College of Life Science, Zhejiang University, Hangzhou, China.
Dov J StekelSchool of Biosciences, The University of Nottingham, Sutton Bonington Campus, Sutton Bonington, Loughborough, LE12 5RD UK.ORCID 0000-0002-2492-8079
Chungui LuSchool of Biosciences, The University of Nottingham, Sutton Bonington Campus, Sutton Bonington, Loughborough, LE12 5RD UK.
T Charlie HodgmanSchool of Biosciences, The University of Nottingham, Sutton Bonington Campus, Sutton Bonington, Loughborough, LE12 5RD UK.ORCID 0000-0001-5862-8296

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phosphorus is a growth-limiting nutrient for plants. The growing scarcity of phosphate stocks threatens global food security. Phosphate-uptake regulation is so complex and incompletely known that attempts to improve phosphorus use efficiency have had extremely limited success. This study improves our understanding of the molecular mechanisms underlying phosphate uptake by investigating the transcriptional dynamics of two regulators: the Ubiquitin ligase PHO2 and the long non-coding RNA IPS1. Temporal measurements of RNA levels have been integrated into mechanistic mathematical models using advanced statistical techniques. Models based solely on current knowledge could not adequately explain the temporal expression profiles. Further modeling and bioinformatics analysis have led to the prediction of three regulatory features: the PHO2 protein mediates the degradation of its own transcriptional activator to maintain constant PHO2 mRNA levels; the binding affinity of the transcriptional activator of

Identifiers

PMID29354282
PMCPMC5758793

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.