Evidence map›Paper›PMID 29354275›Full record

ArticleIUCrJ2018

Active-site solvent replenishment observed during human carbonic anhydrase II catalysis.

Jin Kyun Kim, Carrie L Lomelino, Balendu Sankara Avvaru, Brian P Mahon, Robert McKenna, SangYoun Park, Chae Un Kim

Open access · greenAbstract read
In one paragraph

Article in IUCrJ, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Carbonic anhydrase II microcrystals suitable for XFEL studies.Acta crystallographica. Section F, Structural biology communications · 2018
    Article
  10. Crystallography and Its Impact on Carbonic Anhydrase Research.International journal of medicinal chemistry · 2018
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Jin Kyun KimDepartment of Physics, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea.
Carrie L LomelinoDepartment of Biochemistry and Molecular Biology, College of Medicine, University of Florida, Gainesville, FL 32610, USA.
Balendu Sankara AvvaruDepartment of Biochemistry and Molecular Biology, College of Medicine, University of Florida, Gainesville, FL 32610, USA.
Brian P MahonDepartment of Biochemistry and Molecular Biology, College of Medicine, University of Florida, Gainesville, FL 32610, USA.
Robert McKennaDepartment of Biochemistry and Molecular Biology, College of Medicine, University of Florida, Gainesville, FL 32610, USA.
SangYoun ParkSchool of Systems Biomedical Science, Soongsil University, Seoul 06978, Republic of Korea.
Chae Un KimDepartment of Physics, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea.
University of Florida · USUlsan National Institute of Science and Technology · KRSoongsil University · KR

Funding

Overall (pp. 40-62)P41GM103485 · NIGMS · CORNELL UNIVERSITY · PI CERIONE, RICHARD A. · 2012 to 2018
$15.5M
NIGMS NIH HHS P41 GM103485
6 · The paper itself

Abstract

Human carbonic anhydrase II (hCA II) is a zinc metalloenzyme that catalyzes the reversible hydration/dehydration of CO

Indexed as

active-site solvent replenishmentcarbonic anhydrase IIhigh-pressure cryocoolingproton transferwater dynamics

Identifiers

PMID29354275
PMCPMC5755581
OpenAlexW2777201601

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.